Chlorhexidine
- Generic Name
- Chlorhexidine
- Brand Names
- Betasept, Hibiclens, Instillagel, Nupro Chlorhexidine, Oris, Oro-Clense, Paroex, Perichlor, Peridex, Periochip, Periogard, Prevora, X-pur
- Drug Type
- Small Molecule
- Chemical Formula
- C22H30Cl2N10
- CAS Number
- 55-56-1
- Unique Ingredient Identifier
- R4KO0DY52L
- Background
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings a...
- Indication
Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release "chip" which is inserted into periodo...
- Associated Conditions
- Aphthous ulcer, Catarrh of the throat, Chemotherapy Induced Oral Mucositis, Chronic Wounds, Decubitus Ulcer, Dental Cavity, Dysphagia, Eczema infected, Foeter Ex Ore, Gingival Bleeding, Gingival Diseases, Gingivitis, Glossitis, Hoarseness, Infection, Infectious Periodontal Diseases, Injury Throat, Mild to Moderate Inflammatory Reaction of the Oral Cavity, Mild to Moderate Inflammatory Reaction of the Pharynx, Mouth injury, Mucositis, Neurodermatitis, Ocular Inflammation, Ocular Irritation, Oral Aphthous Ulcer, Pain, Periodontitis, Pharyngitis, Plaque, Dental, Postoperative Wound Infection, Purulent Gingivitis, Radiation Mucositis, Red eye, Ringworm, Skin Infections, Sore Throat, Stomatitis, Surgical Wounds, Tissue Damage, Tonsillitis, Ulcers, Leg, Wound Infections, Bacterial skin infections, Dry, cracked skin, Gum pain, Moderate Gingivitis, Oral infections, Oral lesions, Recurrent Oral fungal infection, Severe Gingivitis, Superficial Wounds, Throat disinfection, Tongue inflammation
- Associated Therapies
- Anesthesia of Mucous Membrane, Antimicrobial Therapy, Contact Lens Care, Disinfection, Disinfection of External Genitalia, Disinfection of the Urethra, Disinfection of the Vaginal Mucosa, Irrigation therapy, Lubrication of the Urethra, Oral Care, Oral Hygiene, Oropharyngeal antisepsis, Promotion of wound healing, Skin disinfection, Surgical Scrubbing, Topical Antisepsis, Urethral Anesthesia, Wound Cleansing, Oral antisepsis, Oral disinfection
Comfort and Antimicrobial Efficacy of Chlorhexidine vs Betadine for Intravitreal Injections
- Conditions
- Interventions
- First Posted Date
- 2018-06-27
- Last Posted Date
- 2018-06-27
- Lead Sponsor
- MidAtlantic Retina
- Target Recruit Count
- 100
- Registration Number
- NCT03571100
- Locations
- 🇺🇸
MidAtlantic Retina, Philadelphia, Pennsylvania, United States
Preventing Diabetic Foot Ulcers Through Cleaner Feet
- First Posted Date
- 2018-04-19
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 175
- Registration Number
- NCT03503370
- Locations
- 🇺🇸
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland, United States
STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)
- First Posted Date
- 2018-04-05
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 42
- Registration Number
- NCT03489629
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States
🇺🇸University of Washington Medical Center and Seattle Children's, Seattle, Washington, United States
Parasitic Ulcer Treatment Trial Pilot
- Conditions
- Interventions
- First Posted Date
- 2018-03-30
- Last Posted Date
- 2024-02-06
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 49
- Registration Number
- NCT03484507
- Locations
- 🇮🇳
Aravind Eye Hospital, Madurai, Tamil Nadu, India
Vaginal Preparation Prior to Hysterectomy
- First Posted Date
- 2018-01-26
- Last Posted Date
- 2021-01-11
- Lead Sponsor
- TriHealth Inc.
- Target Recruit Count
- 94
- Registration Number
- NCT03412734
- Locations
- 🇺🇸
Good Samaritan Hospital, Cincinnati, Ohio, United States
Removal of Bacterial Spores in Adults on Skin
- Conditions
- Interventions
- First Posted Date
- 2017-12-13
- Last Posted Date
- 2018-03-13
- Lead Sponsor
- Caroline Scott
- Target Recruit Count
- 32
- Registration Number
- NCT03372122
- Locations
- 🇺🇸
Bioscience Laboratories, Inc, Bozeman, Montana, United States
Single Dose CHG Pharmacokinetic Study
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Medline Industries
- Target Recruit Count
- 12
- Registration Number
- NCT03331263
- Locations
- 🇺🇸
Algorithme Pharma USA LLC, Fargo, North Dakota, United States
HYPOCHLOROUS ACID SUBSTANTIVITY AS ANTIPLAQUE AGENT (HOCl-SAP)
- Conditions
- Interventions
- First Posted Date
- 2017-06-02
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- Universidad El Bosque, Bogotá
- Target Recruit Count
- 75
- Registration Number
- NCT03174756
- Locations
- 🇨🇴
Gloria Ines Lafaurie, Bogotá, Colombia
S. Aureus Decolonization in HPN Patients.
- First Posted Date
- 2017-06-01
- Last Posted Date
- 2022-05-31
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 63
- Registration Number
- NCT03173053
- Locations
- 🇩🇰
Rigshospitalet, Copenhagen, Denmark
🇩🇰Aalborg Universitetshospital, Aalborg, Denmark
🇳🇱Radboud UMC, Nijmegen, Gelderland, Netherlands
Implant Healing Abutment and Chlorhexidine
- First Posted Date
- 2017-05-05
- Last Posted Date
- 2017-11-28
- Lead Sponsor
- Universidad de Murcia
- Target Recruit Count
- 100
- Registration Number
- NCT03142828
- Locations
- 🇪🇸
Odontologic Universitary Clinic, Murcia, Spain
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.