Ephedrine
- Generic Name
- Ephedrine
- Brand Names
- Akovaz, Bronkaid, Corphedra, Emerphed, Primatene, Rezipres
- Drug Type
- Small Molecule
- Chemical Formula
- C10H15NO
- CAS Number
- 299-42-3
- Unique Ingredient Identifier
- GN83C131XS
- Background
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibitin...
- Indication
Ephedrine intravenous injections are indicated to treat hypotension under anesthesia, ephedrine injections by multiple routes are indicated to treat allergic conditions such as bronchial asthma, ephedrine nasal spray is and OTC medication used as a decongestant.
- Associated Conditions
- Allergic Reaction, Bronchial Asthma, Common Cold, Cough, Depression, Fever, General Anesthesia Induced Hypotension, Headache, Joint Pain, Myasthenia Gravis, Narcolepsy, Nasal Congestion, Rhinorrhoea, Sore Throat, Dry cough
- Associated Therapies
- -
Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia
- First Posted Date
- 2015-12-04
- Last Posted Date
- 2016-11-08
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT02622126
- Locations
- 🇪🇬
Faculty of Medicine, Assiut, Egypt
Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
- Conditions
- Interventions
- First Posted Date
- 2015-09-07
- Last Posted Date
- 2019-01-15
- Lead Sponsor
- Air Force Military Medical University, China
- Target Recruit Count
- 66
- Registration Number
- NCT02542748
- Locations
- 🇨🇳
Xijing Hospital,Fourth Military Medical University, Xi'an, Shaanxi, China
Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2016-01-18
- Lead Sponsor
- Sira Bang
- Target Recruit Count
- 120
- Registration Number
- NCT02522858
- Locations
- 🇰🇷
Inje University Seoul Paik Hospital, Seoul, Korea, Seoul, Jung-Gu,, Korea, Republic of
Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and Kyphoplasty
- Conditions
- Interventions
- First Posted Date
- 2015-06-22
- Last Posted Date
- 2015-06-24
- Lead Sponsor
- Hallym University Medical Center
- Target Recruit Count
- 75
- Registration Number
- NCT02476981
- Locations
- 🇰🇷
Hallym University Sacred Heart Hospital, Anyang-si, Dongan-gu, Korea, Republic of
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2015-06-22
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- University Tunis El Manar
- Target Recruit Count
- 120
- Registration Number
- NCT02477501
- Locations
- 🇹🇳
Tunis maternity and neonatology center, minisetry of public health, Tunis, Tunisia
Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Lagos State Health Service Commission
- Target Recruit Count
- 130
- Registration Number
- NCT02441673
Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in Elderly
- Conditions
- Interventions
- First Posted Date
- 2015-04-28
- Last Posted Date
- 2015-04-28
- Lead Sponsor
- Institut Kassab d'Orthopédie
- Target Recruit Count
- 120
- Registration Number
- NCT02428257
- Locations
- 🇹🇳
Institut Kassab d'Orthopédie, La Manouba, Tunisia
Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
- First Posted Date
- 2015-04-28
- Last Posted Date
- 2018-04-13
- Target Recruit Count
- 1812
- Registration Number
- NCT02428062
- Locations
- 🇮🇹
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico; Via F. Sforza 35, Milano, Italy
Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy
- First Posted Date
- 2014-12-31
- Last Posted Date
- 2018-11-30
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 90
- Registration Number
- NCT02327923
- Locations
- 🇳🇵
BP Koirala Institute of Health Sciences, Dharan, Sunsari District, Nepal
A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability
- Conditions
- Interventions
- First Posted Date
- 2014-10-29
- Last Posted Date
- 2018-03-08
- Lead Sponsor
- KK Women's and Children's Hospital
- Target Recruit Count
- 252
- Registration Number
- NCT02277730
- Locations
- 🇸🇬
KK Women's and Children's Hospital, Singapore, Singapore
Drug Development Updates
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