Nicotine
- Generic Name
- Nicotine
- Brand Names
- Habitrol, Nicoderm C-Q, Nicorelief, Nicorette, Nicotrol
- Drug Type
- Small Molecule
- Chemical Formula
- C10H14N2
- CAS Number
- 54-11-5
- Unique Ingredient Identifier
- 6M3C89ZY6R
- Background
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
- Indication
For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
- Associated Conditions
- Withdrawal Nicotine
- Associated Therapies
- Smoking cessation therapy
Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans
- Conditions
- Interventions
- First Posted Date
- 2008-02-15
- Last Posted Date
- 2014-07-08
- Lead Sponsor
- Yale University
- Target Recruit Count
- 18
- Registration Number
- NCT00616746
- Locations
- 🇺🇸
VA Connecticut Healthcare System, West Haven Campus, West Haven, Connecticut, United States
Nicotine and Behavior in Adult ADHD
- First Posted Date
- 2007-12-14
- Last Posted Date
- 2011-09-09
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 78
- Registration Number
- NCT00573248
- Locations
- 🇺🇸
Department of Pediatrics, Irvine, California, United States
Study of Nicotine for the Prevention of PONV
- First Posted Date
- 2007-11-04
- Last Posted Date
- 2009-09-29
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 200
- Registration Number
- NCT00553709
- Locations
- 🇨🇭
Division of Anesthesiology, Geneva University Hospitals, Geneva, Switzerland
Analysis of Aldehyde Biomarkers of Exposure and Host Response
- Conditions
- Interventions
- First Posted Date
- 2007-06-05
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- University of Nebraska
- Target Recruit Count
- 35
- Registration Number
- NCT00482690
- Locations
- 🇺🇸
Unversity of Nebraska Medical Center, Omaha, Nebraska, United States
Validation of Biomarkers of Exposure and Host Response
- Conditions
- First Posted Date
- 2007-05-02
- Last Posted Date
- 2023-08-31
- Lead Sponsor
- University of Nebraska
- Target Recruit Count
- 60
- Registration Number
- NCT00468234
- Locations
- 🇺🇸
University of Nebraska Medical Center, Omaha, Nebraska, United States
Effect Of Nicotine on Neurocognitive Performance of Cigarette Smokers
- Conditions
- First Posted Date
- 2007-01-31
- Last Posted Date
- 2007-01-31
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 40
- Registration Number
- NCT00429208
- Locations
- 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel
Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer
- First Posted Date
- 2007-01-23
- Last Posted Date
- 2016-01-12
- Lead Sponsor
- Mayo Clinic
- Registration Number
- NCT00425906
Nicotine as an Adjuvant Analgesic for Third Molar Surgery
- First Posted Date
- 2006-10-09
- Last Posted Date
- 2020-11-24
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 20
- Registration Number
- NCT00385216
- Locations
- 🇺🇸
Columbia University, New York, New York, United States
Group Therapy for Nicotine Dependence: Mindfulness and Smoking
- Conditions
- Interventions
- First Posted Date
- 2006-02-28
- Last Posted Date
- 2020-06-16
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 650
- Registration Number
- NCT00297479
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Nicotine Skin Patch in Treating Patients With Kaposi's Sarcoma
- Conditions
- First Posted Date
- 2006-02-24
- Last Posted Date
- 2013-06-20
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 24
- Registration Number
- NCT00295984
- Locations
- 🇺🇸
Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.