Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB
Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...

Associated Conditions
Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
Associated Therapies
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Depression Care Management for Depressed Elders in China Primary Care

Phase 4
Conditions
Interventions
First Posted Date
2011-02-01
Last Posted Date
2011-02-01
Lead Sponsor
Zhejiang University
Target Recruit Count
320
Registration Number
NCT01287494
Locations
🇨🇳

Zhejiang Univeristy, Hangzhou, Zhejiang, China

Bioequivalence Study of Sertraline Hydrochloride Tablets 100 mg Under Fasting Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-12-28
Last Posted Date
2012-01-11
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
32
Registration Number
NCT01267396
Locations
🇮🇳

Veeda Clinical Research (P) Ltd, Ambawadi, Ahmedabad, India

Bioequivalence Study of Sertraline Hydrochloride Tablets 100 mg in Fed Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-12-28
Last Posted Date
2012-01-11
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
32
Registration Number
NCT01267383
Locations
🇮🇳

Veeda Clinical Research (P) Ltd, Ambawadi, Ahmedabad, India

A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-12-01
Last Posted Date
2019-01-04
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
20
Registration Number
NCT01250873
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Daytona Beach, Florida, United States

Pharmacokinetic Properties of Sertraline Before and After Gastric Bypass Surgery

Phase 3
Completed
Conditions
Interventions
First Posted Date
2010-10-05
Last Posted Date
2016-04-06
Lead Sponsor
North Dakota State University
Target Recruit Count
31
Registration Number
NCT01214382
Locations
🇺🇸

Neuropsychiatric Research Institute, Fargo, North Dakota, United States

Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial

First Posted Date
2010-08-10
Last Posted Date
2016-04-08
Lead Sponsor
Research Foundation for Mental Hygiene, Inc.
Target Recruit Count
38
Registration Number
NCT01178671
Locations
🇺🇸

Anxiety Disorders Clinic, New York State Psychiatric Institute, New York, New York, United States

Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents

First Posted Date
2010-07-12
Last Posted Date
2015-05-27
Lead Sponsor
University of Michigan
Target Recruit Count
156
Registration Number
NCT01160588
Locations
🇺🇸

University of Michigan, Ann Arbor, Michigan, United States

The Effects of Treatment With Sertraline for Noncardiac Chest Pain

First Posted Date
2010-04-30
Last Posted Date
2010-05-18
Lead Sponsor
Maastricht University Medical Center
Target Recruit Count
210
Registration Number
NCT01114100
Locations
🇳🇱

Maastricht University Medical Centre, Maastricht, Netherlands

Strategic Use of New Generation Antidepressants for Depression

First Posted Date
2010-04-23
Last Posted Date
2016-10-03
Lead Sponsor
Kyoto University
Target Recruit Count
2011
Registration Number
NCT01109693
Locations
🇯🇵

Nagoya City University Hospital, Nagoya, Aichi, Japan

🇯🇵

Kochi Medical School Hospital, Nangoku, Kochi, Japan

Rhodiola Rosea Therapy of Major Depressive Disorder

First Posted Date
2010-04-02
Last Posted Date
2018-02-22
Lead Sponsor
University of Pennsylvania
Target Recruit Count
58
Registration Number
NCT01098318
Locations
🇺🇸

Depression Research Unit, Philadelphia, Pennsylvania, United States

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