Sulpiride
- Generic Name
- Sulpiride
- Drug Type
- Small Molecule
- Chemical Formula
- C15H23N3O4S
- CAS Number
- 15676-16-1
- Unique Ingredient Identifier
- 7MNE9M8287
- Background
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.
Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in individual European countries.
- Indication
Sulpiride is indicated for the treatment of acute and chronic schizophrenia.
- Associated Conditions
- Acute Schizophrenia, Chronic Schizophrenia, Constipation, Dyspepsia, Menière's Disease, Nausea, Psychosis, Schizophrenia, Vomiting
Dopamine and Cognition
- Conditions
- Interaction of Sulpiride, Average Reward Rate and Cognitive EffortSulpiride's Effect on Striatal BOLD Signal During Working Memory GatingInteraction of Sulpiride, Average Reward Rate and Evidence Accumulation
- Interventions
- Drug: Placebo
- First Posted Date
- 2023-06-01
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- Donders Centre for Cognitive Neuroimaging
- Target Recruit Count
- 47
- Registration Number
- NCT05884671
- Locations
- 🇳🇱
Donders Centre for Cognition, Radboud University, Nijmegen, Gelderland, Netherlands
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement
- Conditions
- Placebo Effect on Mood Improvement
- Interventions
- Drug: PlaceboBehavioral: High expectation manipulationBehavioral: Low expectation manipulation
- First Posted Date
- 2022-01-26
- Last Posted Date
- 2024-01-16
- Lead Sponsor
- Philipps University Marburg Medical Center
- Target Recruit Count
- 297
- Registration Number
- NCT05208294
- Locations
- 🇩🇪
Department of Psychology, Differential Psychology and Personality Research, Philipps-University of Marburg, Marburg, Hessen, Germany
The Effect of Antiemetics on Bowel Preparation Before Colonoscopy
- First Posted Date
- 2020-10-12
- Last Posted Date
- 2020-10-12
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04583111
- Locations
- 🇨🇳
Shengliang Chen, Shanghai, China
Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric
- Conditions
- Menopausal SyndromeHot Flashes
- Interventions
- Drug: Placebo
- First Posted Date
- 2016-04-25
- Last Posted Date
- 2019-01-14
- Lead Sponsor
- Hospital de Clinicas de Porto Alegre
- Target Recruit Count
- 28
- Registration Number
- NCT02749747
- Locations
- 🇧🇷
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil
Pharmacovigilance in Gerontopsychiatric Patients
- Conditions
- DementiaDepressionSchizophreniaPsychosomatic DisordersAnxiety Disorders
- Interventions
- First Posted Date
- 2015-03-02
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- Hannover Medical School
- Target Recruit Count
- 407
- Registration Number
- NCT02374567
- Locations
- 🇩🇪
Bezirkskrankenhaus Augsburg, Augsburg, Germany
🇩🇪Krankenhaus Hedwigshöhe, Berlin, Germany
🇩🇪Hannover Medical School, Hannover, Germany
Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients
- Conditions
- Schizophrenia and Disorders With Psychotic FeaturesSchizoaffective DisordersSchizophrenia
- Interventions
- Drug: Flupentixole
- First Posted Date
- 2014-12-04
- Last Posted Date
- 2018-10-11
- Lead Sponsor
- Technical University of Munich
- Target Recruit Count
- 21
- Registration Number
- NCT02307396
- Locations
- 🇩🇪
Psychiatrische Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Universitaet Muenchen am Klinikum rechts der Isar, Munich, Bavaria, Germany
Interpersonal Psychotherapy for Treatment Resistant Depression
- Conditions
- Treatment Resistant Depression
- Interventions
- Other: IPT+ antidepressant drugs
- First Posted Date
- 2013-07-11
- Last Posted Date
- 2013-07-11
- Lead Sponsor
- Hospital de Clinicas de Porto Alegre
- Target Recruit Count
- 74
- Registration Number
- NCT01896349
- Locations
- 🇧🇷
Federal University of Rio Grande do Sul / Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil
Therapeutic Drug Monitoring and Pharmacokinetic Compartmental Analysis of Sulpiride After Oral Administration to Healthy Volunteers
- First Posted Date
- 2013-01-29
- Last Posted Date
- 2013-01-29
- Lead Sponsor
- Damanhour University
- Target Recruit Count
- 16
- Registration Number
- NCT01777685
- Locations
- 🇪🇬
Pharmaceutics Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt
Dopaminergic Modulation of Choroidal Blood Flow Changes During Dark/Light Transitions
- Conditions
- Regional Blood FlowOcular Physiology
- Interventions
- First Posted Date
- 2006-01-23
- Last Posted Date
- 2008-07-09
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 21
- Registration Number
- NCT00280501
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Vienna, Austria
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.