Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Efficacy Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder
- Conditions
- Interventions
- First Posted Date
- 2009-12-16
- Last Posted Date
- 2011-12-06
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 120
- Registration Number
- NCT01033084
- Locations
- 🇧🇷
University of Sao Paulo, Sao Paulo, SP, Brazil
An 8-week, Open-label Study to Evaluate the Effect of Sertraline on Polysomnogram in Depressive Patients With Insomnia
- First Posted Date
- 2009-12-15
- Last Posted Date
- 2015-05-04
- Lead Sponsor
- Guang Dong Provincial Mental Health Institute
- Target Recruit Count
- 31
- Registration Number
- NCT01032434
- Locations
- 🇨🇳
Guangdong Provincial Mental Health Institute, Guang Zhou, Guangdong, China
Treatment of Postpartum Depression With Psychotherapy and Add-on Sertraline
- Conditions
- Interventions
- First Posted Date
- 2009-12-09
- Last Posted Date
- 2011-05-10
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 42
- Registration Number
- NCT01028482
- Locations
- 🇮🇱
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
fMRI Study of Treatment Changes in Major Depression
- Conditions
- Interventions
- First Posted Date
- 2009-12-08
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 97
- Registration Number
- NCT01027559
- Locations
- 🇺🇸
Washington University, Saint Louis, Missouri, United States
Pharmacokinetics and Pharmacodynamics of Sertraline After Low Dose Administration
- First Posted Date
- 2009-09-01
- Last Posted Date
- 2011-01-11
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 10
- Registration Number
- NCT00969852
- Locations
- 🇰🇷
Clinical Trials Center, Seoul National University Hospital, Seoul, Korea, Republic of
Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms
- Conditions
- Interventions
- First Posted Date
- 2009-08-10
- Last Posted Date
- 2017-04-20
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT00955474
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Chronic Kidney Disease Antidepressant Sertraline Trial
- Conditions
- Interventions
- First Posted Date
- 2009-07-27
- Last Posted Date
- 2018-03-09
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 201
- Registration Number
- NCT00946998
- Locations
- 🇺🇸
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas, United States
🇺🇸University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States
Bioequivalence Study of Sertraline 100 mg Tablet and ZOLOFT Following a 100 mg Dose in Healthy Subjects Under Fasting Conditions
- Conditions
- First Posted Date
- 2009-07-23
- Last Posted Date
- 2009-07-23
- Lead Sponsor
- Torrent Pharmaceuticals Limited
- Registration Number
- NCT00944242
- Locations
- 🇨🇦
Anapharm Inc., Montreal, Quebec, Canada
The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants
- Conditions
- Interventions
- First Posted Date
- 2009-06-10
- Last Posted Date
- 2014-06-18
- Lead Sponsor
- Caecilie Buhmann
- Target Recruit Count
- 280
- Registration Number
- NCT00917397
- Locations
- 🇩🇰
Psykiatrisk Center Gentofte, Hellerup, Denmark
Identifying Brain and Genetic Markers of Sertraline Treatment Response in People With Social Anxiety Disorder
- First Posted Date
- 2009-03-31
- Last Posted Date
- 2011-11-23
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 200
- Registration Number
- NCT00872131
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.