Gabapentin

Generic Name
Gabapentin
Brand Names
Gralise, Neurontin
Drug Type
Small Molecule
Chemical Formula
C9H17NO2
CAS Number
60142-96-3
Unique Ingredient Identifier
6CW7F3G59X
Background

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication

In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions
Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
Associated Therapies
-

Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery

First Posted Date
2022-06-10
Last Posted Date
2022-06-10
Lead Sponsor
University of Puerto Rico
Target Recruit Count
100
Registration Number
NCT05413902
Locations
🇵🇷

Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico

Effect of Milnacipran / Gabapentin in Fibromyalgia

First Posted Date
2022-05-20
Last Posted Date
2022-05-20
Lead Sponsor
Mansoura University
Target Recruit Count
75
Registration Number
NCT05384210
Locations
🇪🇬

Mansoura University, Mansoura, DK, Egypt

Feasibility of Early Gabapentin as an Intervention for Neurorecovery

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2022-03-31
Last Posted Date
2024-06-13
Lead Sponsor
MetroHealth Medical Center
Target Recruit Count
42
Registration Number
NCT05302999
Locations
🇺🇸

MetroHealth Medical Center, Cleveland, Ohio, United States

Botulinum Toxin Type A in Diabetic Peripheral Neuropathy

First Posted Date
2022-03-25
Last Posted Date
2022-04-06
Lead Sponsor
Alexandria University
Target Recruit Count
30
Registration Number
NCT05296759
Locations
🇪🇬

faculty of medicine Alexandria university, Alexandria, Egypt

Gabapentin Dosages for Postoperative Analgesia Following Open Thoracotomy

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2021-12-29
Last Posted Date
2024-03-21
Lead Sponsor
Indiana University
Target Recruit Count
20
Registration Number
NCT05172570
Locations
🇺🇸

indiana University, Indianapolis, Indiana, United States

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

First Posted Date
2021-12-14
Last Posted Date
2024-10-21
Lead Sponsor
Natalie Lockney
Target Recruit Count
64
Registration Number
NCT05156060
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

Gabapentin for the Reduction of Opiate Use Following Pulmonary Resection (GROUP Trial)

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2021-10-29
Last Posted Date
2023-04-13
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT05100160
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures

First Posted Date
2021-10-13
Last Posted Date
2024-06-18
Lead Sponsor
Mayo Clinic
Target Recruit Count
188
Registration Number
NCT05076110
Locations
🇺🇸

Mayo clinic, Rochester, Minnesota, United States

Biomarker-Driven Pharmacological Treatment of Adolescents With Autism Spectrum Disorder With Gabapentin

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2021-10-01
Last Posted Date
2024-05-16
Lead Sponsor
David Cochran
Target Recruit Count
40
Registration Number
NCT05063656
Locations
🇺🇸

University of Massachusetts Medical School, Worcester, Massachusetts, United States

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

First Posted Date
2021-10-01
Last Posted Date
2024-07-10
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
68
Registration Number
NCT05064319
Locations
🇺🇸

Medical University Of South Carolina, Charleston, South Carolina, United States

© Copyright 2024. All Rights Reserved by MedPath