Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
The Effects of Dexmedetomidine on Peroperative Shivering Incidence Under Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2013-08-13
- Last Posted Date
- 2013-08-13
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 120
- Registration Number
- NCT01921361
- Locations
- 🇹🇷
Erciyes University, Kayseri, Turkey
Dexmedetomidine on Pediatric Heart Operation
- Conditions
- Interventions
- First Posted Date
- 2013-08-12
- Last Posted Date
- 2016-11-10
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT01920542
- Locations
- 🇰🇷
Gachon University Gil Medical Cneter, Incheon, Korea, Republic of
Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery
- First Posted Date
- 2013-08-08
- Last Posted Date
- 2013-08-08
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 60
- Registration Number
- NCT01918917
Bradycardia Following Intraoperative Administration of Dexmedetomidine
- First Posted Date
- 2013-08-06
- Last Posted Date
- 2016-10-27
- Lead Sponsor
- Joseph D. Tobias
- Target Recruit Count
- 921
- Registration Number
- NCT01917097
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics
- Conditions
- Interventions
- First Posted Date
- 2013-08-02
- Last Posted Date
- 2018-03-23
- Lead Sponsor
- Carelon Research
- Target Recruit Count
- 119
- Registration Number
- NCT01915277
- Locations
- 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
🇺🇸Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸Boston Children's Hospital, Boston, Massachusetts, United States
Dexmedetomidine to Prevent Agitation After Free Flap Surgery
- First Posted Date
- 2013-07-22
- Last Posted Date
- 2014-11-13
- Lead Sponsor
- Peking University
- Target Recruit Count
- 80
- Registration Number
- NCT01904760
- Locations
- 🇨🇳
School and Hospital of Stomatology, Beijing, Beijing, China
Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery
- Conditions
- Interventions
- First Posted Date
- 2013-07-17
- Last Posted Date
- 2016-07-11
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 63
- Registration Number
- NCT01901588
- Locations
- 🇺🇸
NYU Langone Medical Center, New York, New York, United States
Intranasal Dexmedetomidine Sedation for Pediatric CT Imaging
- Conditions
- Interventions
- First Posted Date
- 2013-07-16
- Last Posted Date
- 2013-07-16
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 60
- Registration Number
- NCT01900405
- Locations
- 🇧🇷
University Hospital, University of Sao Paulo, Sao Paulo, SP, Brazil
The Effect of Dexmedetomidine in Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
- Conditions
- Interventions
- First Posted Date
- 2013-07-12
- Last Posted Date
- 2014-01-27
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 70
- Registration Number
- NCT01898819
Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
- Conditions
- Interventions
- First Posted Date
- 2013-07-10
- Last Posted Date
- 2015-01-06
- Lead Sponsor
- Yao Yusheng
- Target Recruit Count
- 156
- Registration Number
- NCT01895023
- Locations
- 🇨🇳
Fujian Provincial Hospital, Fuzhou, Fujian, China
Drug Development Updates
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