Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
The Neural Mechanisms of Anesthesia and Human Consciousness
- Conditions
- Interventions
- First Posted Date
- 2013-06-28
- Last Posted Date
- 2016-01-11
- Lead Sponsor
- University of Turku
- Target Recruit Count
- 47
- Registration Number
- NCT01889004
- Locations
- 🇫🇮
Turku PET Centre, Turku, Finland
Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
- First Posted Date
- 2013-06-26
- Last Posted Date
- 2024-07-11
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 50
- Registration Number
- NCT01887184
The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery
- First Posted Date
- 2013-06-25
- Last Posted Date
- 2013-06-25
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 200
- Registration Number
- NCT01886079
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of
The Effects of Dexmedetomidine to Postoperative Awakening and Extubation-related Changes in Blood Pressure
- First Posted Date
- 2013-06-06
- Last Posted Date
- 2017-05-05
- Lead Sponsor
- Tampere University Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT01871129
- Locations
- 🇫🇮
TAYS Sydänkeskus Oy (Heart Center CO. Tampere University Hospital), Tampere, Finland
Pharmacokinetics of Dexmedetomidine in Morbid Obesity
- First Posted Date
- 2013-05-29
- Last Posted Date
- 2015-03-12
- Target Recruit Count
- 20
- Registration Number
- NCT01864187
- Locations
- 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China
Dexmedetomidine for Laryngeal Mask Airway Insertion
- Conditions
- Interventions
- First Posted Date
- 2013-05-13
- Last Posted Date
- 2014-04-22
- Lead Sponsor
- Ajou University School of Medicine
- Target Recruit Count
- 22
- Registration Number
- NCT01852539
- Locations
- 🇰🇷
Ajou University School of Medicine, Suwon, Korea, Republic of
Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
- First Posted Date
- 2013-05-10
- Last Posted Date
- 2014-03-19
- Lead Sponsor
- Chosun University Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT01851005
- Locations
- 🇰🇷
Chosun University Hospital, Gwangju, Korea, Republic of
Study of Dexmedetomidine in Spine Surgery
- Conditions
- Interventions
- First Posted Date
- 2013-05-09
- Last Posted Date
- 2017-05-05
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 142
- Registration Number
- NCT01850017
- Locations
- 🇺🇸
University of Virginia, Charlottesville, Virginia, United States
Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
- Conditions
- Interventions
- First Posted Date
- 2013-05-03
- Last Posted Date
- 2022-12-28
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 7
- Registration Number
- NCT01845441
- Locations
- 🇺🇸
University Hospitals of Cleveland, Cleveland, Ohio, United States
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
- First Posted Date
- 2013-04-25
- Last Posted Date
- 2014-02-07
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 108
- Registration Number
- NCT01840254
- Locations
- 🇰🇷
Yonsei University College of Medicine, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.