Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block

First Posted Date
2013-11-11
Last Posted Date
2019-05-29
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
100
Registration Number
NCT01981369
Locations
🇨🇦

Saint Joseph's Health Care London, London, Ontario, Canada

Safety Study of Dexmedetomidine in Septic Patients

Not Applicable
Completed
Conditions
Sepsis
Agitation
Interventions
Drug: Dexmedetomidine
First Posted Date
2013-11-06
Last Posted Date
2022-03-22
Lead Sponsor
First Affiliated Hospital of Zhejiang University
Target Recruit Count
40
Registration Number
NCT01976754
Locations
🇨🇳

Zhanqin Zhang, Hangzhou, Zhejiang, China

Placebo Controlled Clinical Trial of the Postoperative Opioid Sparing Effects of Intraoperative Dexmedetomidine Infusion for Thoracic Surgery

Phase 3
Completed
Conditions
Pain
Interventions
Drug: Dexmedetomidine
Drug: Placebo
First Posted Date
2013-10-31
Last Posted Date
2024-02-20
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
333
Registration Number
NCT01973452
Locations
🇺🇸

Memorial Sloan Kettering Westchester, Harrison, New York, United States

🇺🇸

Memorial Sloan Kettering Cancer Center at Basking Ridge, Basking Ridge, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Cancer Center 1275 York Avenue, New York, New York, United States

and more 1 locations

Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.

First Posted Date
2013-10-17
Last Posted Date
2013-10-17
Lead Sponsor
TC Erciyes University
Target Recruit Count
60
Registration Number
NCT01964586

Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus

First Posted Date
2013-10-16
Last Posted Date
2014-09-18
Lead Sponsor
Guangzhou General Hospital of Guangzhou Military Command
Target Recruit Count
80
Registration Number
NCT01963546
Locations
🇨🇳

The General Hospital Of Guangzhou Military Command, Guangzhou, Guangdong, China

Controlled Hypotension During Functional Endoscopic Sinus Surgery

Phase 4
Completed
Conditions
Hemorrhage
Interventions
Drug: Magnesium Sulfate
Drug: Dexmedetomidine
First Posted Date
2013-10-08
Last Posted Date
2013-10-08
Lead Sponsor
TC Erciyes University
Target Recruit Count
60
Registration Number
NCT01956981

The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients

First Posted Date
2013-09-23
Last Posted Date
2013-09-23
Lead Sponsor
TC Erciyes University
Target Recruit Count
60
Registration Number
NCT01948336

Intramuscular Dexmedetomidine as Premedication

First Posted Date
2013-09-09
Last Posted Date
2013-09-09
Lead Sponsor
Guangzhou First People's Hospital
Target Recruit Count
40
Registration Number
NCT01937611
Locations
🇨🇳

Affiliated First People's Hospital of Guangzhou, Guangzhou Medical University, Guangzhou, Guangdong, China

Postoperative Analgesic Effect Of Dexmedetomidine Administration in Wound Infiltration for Total Abdominal Hysterectomy

Phase 4
Completed
Conditions
Pain
Interventions
Drug: Dexmedetomidine
Drug: Levobupivacaine
First Posted Date
2013-08-27
Last Posted Date
2013-08-27
Lead Sponsor
TC Erciyes University
Target Recruit Count
50
Registration Number
NCT01929252
Locations
🇹🇷

Erciyes university hospital, Kayseri, Turkey

Dexmedetomidine for Reversal of Cocaine's Effects on the Heart

First Posted Date
2013-08-22
Last Posted Date
2020-01-14
Lead Sponsor
Cedars-Sinai Medical Center
Target Recruit Count
115
Registration Number
NCT01927640
Locations
🇺🇸

Cedars-Sinai, Los Angeles, California, United States

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