Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Transverse Abdominal Block for Analgesia in Casarean Section
- Conditions
- Interventions
- First Posted Date
- 2014-04-24
- Last Posted Date
- 2014-12-16
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 120
- Registration Number
- NCT02122510
- Locations
- 🇪🇬
Tanta University Hospitals, Tanta, Algharbiya, Egypt
The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis
- Conditions
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2019-03-04
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 12
- Registration Number
- NCT02109965
- Locations
- 🇨🇳
National Taiwan University Hospital, Taipei, Taiwan
Intranasal Dexmedetomidine Premedication
- Conditions
- Interventions
- First Posted Date
- 2014-04-09
- Last Posted Date
- 2016-03-14
- Lead Sponsor
- Guangzhou First People's Hospital
- Target Recruit Count
- 81
- Registration Number
- NCT02108171
- Locations
- 🇨🇳
Guangzhou First Municipal People's Hospital, Guangzhou, China
Comparison of Preemptive Analgesic Effects of Dexketoprofen Versus Dexmedetomidine on Abdominal Hysterectomy Patients
- First Posted Date
- 2014-03-19
- Last Posted Date
- 2014-03-21
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 60
- Registration Number
- NCT02092012
- Locations
- 🇹🇷
Erciyes Univercity Medicine Faculty, Kayseri, Turkey
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2014-03-11
- Last Posted Date
- 2014-03-11
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 40
- Registration Number
- NCT02083055
- Locations
- 🇹🇭
Faculty of dentistry, Mahidol university, Rajthevi, Bangkok, Thailand
Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients
- First Posted Date
- 2014-03-06
- Last Posted Date
- 2014-03-06
- Lead Sponsor
- Qilu Hospital of Shandong University
- Target Recruit Count
- 600
- Registration Number
- NCT02080169
- Locations
- 🇨🇳
Department ICU, Shandong university affiliated Qilu Hospital., Jinan, Shandong, China
Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients
- Conditions
- Interventions
- First Posted Date
- 2014-02-26
- Last Posted Date
- 2015-04-14
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 60
- Registration Number
- NCT02072083
- Locations
- 🇹🇷
Erciyes university hospital, Kayseri, Turkey
Lidocaine Combined Dexmedetomidine for Obturator Nerve Block
- First Posted Date
- 2014-02-19
- Last Posted Date
- 2014-12-22
- Lead Sponsor
- Guolin Wang
- Target Recruit Count
- 60
- Registration Number
- NCT02066727
- Locations
- 🇨🇳
Tainjin Medical University General Hospita& the Second Hospital, Tianjin, Tianjin, China
Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane Block
- Conditions
- Interventions
- First Posted Date
- 2014-02-17
- Last Posted Date
- 2015-09-14
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 90
- Registration Number
- NCT02064530
- Locations
- 🇹🇷
Erciyes universty, Kayseri, Melikgazi, Turkey
The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea
- Conditions
- Interventions
- First Posted Date
- 2014-02-13
- Last Posted Date
- 2014-11-10
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 47
- Registration Number
- NCT02062333
- Locations
- 🇹🇷
Kayseri Education and Research Hospital, Kayseri, Turkey
Drug Development Updates
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