Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
A Comparison of Sedative Drugs for Conscious Sedation During Ultrasound Guided Transbronchial Needle Aspiration
- Conditions
- Interventions
- First Posted Date
- 2014-06-06
- Last Posted Date
- 2017-05-19
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT02157818
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Dexmedetomidine in Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2014-06-04
- Last Posted Date
- 2016-09-26
- Lead Sponsor
- Inje University
- Target Recruit Count
- 74
- Registration Number
- NCT02155010
- Locations
- 🇰🇷
Inje University, Haeundae paik hospital, Busan, Korea, Republic of
Dexmedetomidine Influence on the Level of Perioperative Blood Glucose and Insulin of Elderly Diabetes Patients
- First Posted Date
- 2014-06-03
- Last Posted Date
- 2014-06-03
- Target Recruit Count
- 92
- Registration Number
- NCT02154074
- Locations
- 🇨🇳
SecondXianJiaotongU, Xi'an, Shanxi, China
Dexmedetomidine-ketamine in Femur Proximal Fracture Patients
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2019-04-29
- Lead Sponsor
- Inje University
- Target Recruit Count
- 46
- Registration Number
- NCT02150759
- Locations
- 🇰🇷
Haeundae paik hospital, inje university, Busan, Korea, Republic of
Postoperative Sleep Quality of Patients Sedation With i.v. Dexmedetomidine or Midazolam Undergoing TURP
- Conditions
- Interventions
- First Posted Date
- 2014-05-20
- Last Posted Date
- 2015-09-24
- Lead Sponsor
- China Medical University, China
- Target Recruit Count
- 111
- Registration Number
- NCT02142595
- Locations
- 🇨🇳
the First Hospital of China Medical University, Shenyang, Liaoning, China
Efficacy of Dexmedetomidine in Preventing Contrast Induced Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2014-05-14
- Last Posted Date
- 2014-05-14
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 60
- Registration Number
- NCT02137863
Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients
- First Posted Date
- 2014-05-08
- Last Posted Date
- 2014-07-11
- Lead Sponsor
- Tang-Du Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT02134093
Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidine
- Conditions
- Interventions
- First Posted Date
- 2014-05-02
- Last Posted Date
- 2021-07-14
- Lead Sponsor
- University of Louisville
- Target Recruit Count
- 21
- Registration Number
- NCT02129426
- Locations
- 🇺🇸
University of Louisville, Louisville, Kentucky, United States
The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery
- First Posted Date
- 2014-04-25
- Last Posted Date
- 2014-04-25
- Lead Sponsor
- Shaanxi Provincial People's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02123355
Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in ICU.
- First Posted Date
- 2014-04-24
- Last Posted Date
- 2014-04-24
- Lead Sponsor
- Tianjin Third Central Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT02122055
Drug Development Updates
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