Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate
- First Posted Date
- 2010-10-20
- Last Posted Date
- 2011-04-28
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 51
- Registration Number
- NCT01224470
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
The Effects of Dexmedetomidine and Propofol on Cerebral Blood Flow and Brain Oxygenation During Deep Brain Stimulation
- Conditions
- Interventions
- First Posted Date
- 2010-09-13
- Last Posted Date
- 2016-12-14
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 44
- Registration Number
- NCT01200433
- Locations
- 🇺🇸
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial Cystitis
- Conditions
- Interventions
- First Posted Date
- 2010-09-03
- Last Posted Date
- 2015-04-15
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 41
- Registration Number
- NCT01195116
- Locations
- 🇺🇸
University of Rochester Medical Center, Rochester, New York, United States
Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement
- Conditions
- Interventions
- First Posted Date
- 2010-08-25
- Last Posted Date
- 2014-04-01
- Lead Sponsor
- Nationwide Children's Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT01188551
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
Effect of Dexmedetomidine on Microcirculation in Patients Undergoing Extracorporeal Shock Wave Lithotripsy
- Conditions
- First Posted Date
- 2010-08-11
- Last Posted Date
- 2012-12-10
- Lead Sponsor
- National Taiwan University Hospital
- Registration Number
- NCT01179438
- Locations
- 🇨🇳
National Taiwan University Hospital, anesthesiology department, Taipei, Taiwan
Study to Evaluate Hemodynamic Effect of Different Loading Doses of Precedex in Post-surgical Intensive Care Unit (ICU) Patients
- First Posted Date
- 2010-07-26
- Last Posted Date
- 2015-07-24
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 373
- Registration Number
- NCT01169571
- Locations
- 🇨🇦
Foothills Medical Centre, University of Calgary, Calgary, Alberta, Canada
🇨🇦University of Alberta Hospital, Department of Anesthesiology and Pain Medicine, Edmonton, Alberta, Canada
🇨🇦Red Deer Regional Hospital Centre, Alberta Health Services, Red Deer, Alberta, Canada
Safety, Efficacy and Pharmacokinetic Study of Dexmedetomidine in Pediatrics Ages ≥28 Weeks to ≤44 Weeks Gestational Age
- Conditions
- Interventions
- First Posted Date
- 2010-07-09
- Last Posted Date
- 2015-08-13
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 36
- Registration Number
- NCT01159262
- Locations
- 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States
🇺🇸Georgia Health Sciences University, Augusta, Georgia, United States
🇺🇸Loyola University Medical Center, Maywood, Illinois, United States
Comparing Safety and Efficacy of Dexmedetomidine and Propofol
- Conditions
- Interventions
- First Posted Date
- 2010-06-29
- Last Posted Date
- 2019-05-21
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 15
- Registration Number
- NCT01152021
- Locations
- 🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States
Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
- First Posted Date
- 2010-06-29
- Last Posted Date
- 2015-01-21
- Lead Sponsor
- Austin Health
- Target Recruit Count
- 96
- Registration Number
- NCT01151865
- Locations
- 🇦🇺
Austin Hospital, Melbourne, Victoria, Australia
🇦🇺Royal North Shore Hospital, St Leonards, New South Wales, Australia
🇦🇺Royal Perth Hospital, Perth, Western Australia, Australia
Dexmedetomidine for the Treatment of Delirium After Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2010-06-09
- Last Posted Date
- 2016-11-01
- Lead Sponsor
- Thorax-Kärlkliniken
- Target Recruit Count
- 3
- Registration Number
- NCT01140529
- Locations
- 🇸🇪
ThoraxKärlkliniken, Universitetssjukhuset, Linköping, Sweden
Drug Development Updates
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