Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Dexmedetomidine in Seizure Patients
- Conditions
- First Posted Date
- 2010-05-05
- Last Posted Date
- 2013-08-09
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 16
- Registration Number
- NCT01116700
- Locations
- 🇺🇸
University of California San Francisco, San Francisco, California, United States
Dexmedetomidine Versus Midazolam for Intensive Care Sedation of Children
- First Posted Date
- 2010-03-24
- Last Posted Date
- 2011-07-21
- Lead Sponsor
- Ullevaal University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT01091818
- Locations
- 🇳🇴
Dept of Anesthesiology, Oslo University Hospital, Ullevaal, Oslo, Norway
Sedation to Electroencephalography With Dexmedetomidine or Chloral Hydrate
- Conditions
- Interventions
- First Posted Date
- 2010-03-10
- Last Posted Date
- 2013-10-25
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 25
- Registration Number
- NCT01083797
- Locations
- 🇧🇷
Santa Casa de Belo Horizonte, Belo Horizonte, Minas Gerais, Brazil
Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit
- Conditions
- Interventions
- First Posted Date
- 2010-03-10
- Last Posted Date
- 2010-06-04
- Lead Sponsor
- University of Turku
- Target Recruit Count
- 12
- Registration Number
- NCT01084473
- Locations
- 🇫🇮
Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University and Turku University Hospital, Turku, Finland
Dexmedetomidine-propofol-remifentanil Anaesthesia and Reactivity to Noxious Stimuli
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2013-10-09
- Lead Sponsor
- Arvi Yli-Hankala
- Target Recruit Count
- 44
- Registration Number
- NCT01076790
- Locations
- 🇫🇮
Tampere University Hospital, Tampere, Finland
Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure
- Conditions
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2011-10-04
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 1
- Registration Number
- NCT01076816
- Locations
- 🇧🇪
University Hospital Ghent, Ghent, Belgium
🇧🇪Cliniques Universitaires Saint-Luc, Brussels, Belgium
Sedation With Dexmedetomidine During Cardiac Catheterization
- First Posted Date
- 2010-02-22
- Last Posted Date
- 2019-04-16
- Lead Sponsor
- Aruna Nathan
- Target Recruit Count
- 4
- Registration Number
- NCT01072643
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Dexmedetomidine Versus Placebo in Endoscopic Retrograde Cholangiopancreatography (ERCP) Sedation
- First Posted Date
- 2010-02-18
- Last Posted Date
- 2012-07-16
- Lead Sponsor
- Helsinki University Central Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT01070680
- Locations
- 🇫🇮
Helsinki University Central Hospital,Meilahti hospital,Endoscopy unit, Helsinki, Uusimaa, Finland
Comparison of Two Doses of Intranasal Dexmedetomidine as Premedication in Children
- Conditions
- Interventions
- First Posted Date
- 2010-02-09
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 104
- Registration Number
- NCT01065701
- Locations
- 🇭🇰
QUeen Mary Hospital, Hong Kong, Hong Kong
Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)
- Conditions
- Interventions
- First Posted Date
- 2010-02-01
- Last Posted Date
- 2018-07-03
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 41
- Registration Number
- NCT01059929
- Locations
- 🇺🇸
The University of Chicago Medical Center, Chicago, Illinois, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.