Metronidazole

Generic Name: Metronidazole

Brand Names: Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole

Drug Type: Small Molecule

Chemical Formula: C_₆H_₉N_₃O_₃

CAS Number: 443-48-1

Unique Ingredient Identifier: 140QMO216E

Background: Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication: Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions: Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis

Associated Therapies: -

Clinical Trials

Levofloxacin-containing Therapies In Second Line Helicobacter Pylori Eradication

Not Applicable

Completed

Conditions: Helicobacter Pylori Infection

Interventions: Drug: Nexium
Drug: Amolin
Drug: Cravit
Drug: Flagyl

First Posted Date: 2015-11-04

Last Posted Date: 2017-02-28

Lead Sponsor: Chang Gung Memorial Hospital

Target Recruit Count: 164

Registration Number: NCT02596620

Once Daily Metronidazole for Perforated Appendicitis

Phase 4

Withdrawn

Conditions: Appendicitis

Interventions: Drug: Metronidazole

First Posted Date: 2015-09-25

Last Posted Date: 2017-07-21

Lead Sponsor: Ahmed Nasr

Registration Number: NCT02561117

Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunology

Phase 1

Completed

Conditions: Bacterial Vaginosis
HIV Infections

Interventions: Drug: Metronidazole

First Posted Date: 2015-08-19

Last Posted Date: 2016-02-10

Lead Sponsor: University of Toronto

Target Recruit Count: 50

Registration Number: NCT02527941

Locations: 🇰🇪
Kenya AIDS Vaccine Initiative Clinic, Nairobi, Kenya

Evaluation of Safety,Pharmacokinetics and Efficacy of CAZ-AVI With Metronidazole in Children Aged 3 Months to 18 Years Old With Complicated Intra-abdominal Infections (cIAIs).

Phase 2

Completed

Conditions: Complicated Intra-abdominal Infections

Interventions: Drug: Ceftazidime -avibactam
Drug: Meropenem
Drug: Metronidazole

First Posted Date: 2015-06-19

Last Posted Date: 2018-08-09

Lead Sponsor: Pfizer

Target Recruit Count: 83

Registration Number: NCT02475733

Locations: 🇺🇸
CHOC Children's, Orange, California, United States
🇨🇿
Oblastni Nemocnice Kolin, a.s., Nemocnice Stredoceskeho Kraje, Detske oddeleni, Kolin III, Czechia
🇺🇸
Rady Children's Hospital San Diego, San Diego, California, United States

and more 32 locations