Pregabalin
- Generic Name
- Pregabalin
- Brand Names
- Lyrica, Pregabalin Accord, Pregabalin Pfizer, Pregabalin Sandoz, Pregabalin Mylan, Pregabalin Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H17NO2
- CAS Number
- 148553-50-8
- Unique Ingredient Identifier
- 55JG375S6M
- Background
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by bind...
- Indication
Pregabalin is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury, and as adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older.
- Associated Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Epilepsies, Fibromyalgia, Generalized Anxiety Disorder, Neuropathic Pain, Partial-Onset Seizures, Peripheral Neuropathic Pain, Peripheral neuropathy, Postherpetic Neuralgia
- Associated Therapies
- -
Melatonin vs Pregabalin for Anxiolysis and Sedation
- First Posted Date
- 2022-02-02
- Last Posted Date
- 2022-12-21
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 78
- Registration Number
- NCT05221151
- Locations
- 🇪🇬
Faculty of Medicine, University Hospitals, Shibīn Al Kawm, Menoufia, Egypt
Study to Investigate the Pharmacodynamic Effects of IP2015 in Healthy Male Subjects Using the Intradermal Capsaicin Model
- Conditions
- Interventions
- First Posted Date
- 2022-01-06
- Last Posted Date
- 2022-01-06
- Lead Sponsor
- Initiator Pharma
- Target Recruit Count
- 24
- Registration Number
- NCT05181852
The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia
- Conditions
- Interventions
- First Posted Date
- 2021-08-25
- Last Posted Date
- 2023-08-15
- Lead Sponsor
- Marmara University
- Target Recruit Count
- 40
- Registration Number
- NCT05020600
- Locations
- 🇹🇷
Feyza Nur YUCEL, İstanbul, Turkey
Combination of Duloxetine and Pregabalin to Improve Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2021-04-28
- Last Posted Date
- 2021-04-28
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 72
- Registration Number
- NCT04862845
Duloxetine vs Pregabalin for Thoracotomy Pain
- First Posted Date
- 2021-03-04
- Last Posted Date
- 2021-06-02
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 75
- Registration Number
- NCT04782310
- Locations
- 🇪🇬
Bassant abdelhamid, Cairo, Egypt
PROUD Study - Preventing Opioid Use Disorders
- Conditions
- Interventions
- Behavioral: Guided mindfulness exercisesOther: Self-administered aromatherapyDrug: Baby aspirinDrug: Tylenol/AcetaminophenDrug: PregabalinDrug: PrednisoneDrug: MeloxicamDrug: PrilosecDrug: TramadolDrug: VoltarenDrug: ZofranDrug: PepcidDrug: ReglanDrug: VersedDrug: LidocaineDrug: PropofolDrug: AncefDrug: Tranexamic Acid (TXA)Drug: DecadronDrug: Bupivacaine hydrochlorideDrug: Toradol
- First Posted Date
- 2021-02-23
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Emory University
- Target Recruit Count
- 57
- Registration Number
- NCT04766996
- Locations
- 🇺🇸
Emory University Orthopaedic and Spine Hospital, Atlanta, Georgia, United States
PHOTOTHERAPY VERSUS PREGABALIN IN TREATMENT OF REFRACTORY UREAMIC PRURITIS
- First Posted Date
- 2020-12-09
- Last Posted Date
- 2021-07-26
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 40
- Registration Number
- NCT04660773
- Locations
- 🇪🇬
Faculty of Medicine, Alexandria, Egypt
A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain
- Conditions
- Interventions
- First Posted Date
- 2020-11-23
- Last Posted Date
- 2022-12-12
- Lead Sponsor
- Bayer
- Target Recruit Count
- 154
- Registration Number
- NCT04641273
- Locations
- 🇩🇰
Kolding Sygehus, Kolding, Denmark
🇨🇿NEUROHK s.r.o, Chocen, Czechia
🇨🇿Vestra Clinics s.r.o., Rychnov nad Kneznou, Czechia
Comparison of the Efficacy of Duloxetine and Pregabalin in Patients With Knee Osteoarthritis With Mix Type Pain
- First Posted Date
- 2020-08-31
- Last Posted Date
- 2021-01-25
- Target Recruit Count
- 66
- Registration Number
- NCT04532684
A Phase 2 Study to Evaluate Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing Bunionectomy
- Conditions
- Interventions
- First Posted Date
- 2020-07-31
- Last Posted Date
- 2021-11-23
- Lead Sponsor
- Nevakar, Inc.
- Target Recruit Count
- 87
- Registration Number
- NCT04495283
- Locations
- 🇺🇸
Lotus HD Research, Bellaire, Texas, United States
🇺🇸Lotus Clinical Resarch,LLC, Pasadena, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.