Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy

A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

First Posted Date
2022-05-03
Last Posted Date
2024-05-16
Lead Sponsor
Mayo Clinic
Target Recruit Count
220
Registration Number
NCT05357690
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2022-04-22
Last Posted Date
2022-07-19
Lead Sponsor
Sohag University
Target Recruit Count
80
Registration Number
NCT05341323
Locations
🇪🇬

Sohag Faculty of Medicine, Sohag, Egypt

Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery

First Posted Date
2022-04-18
Last Posted Date
2022-04-18
Lead Sponsor
Ataturk University
Target Recruit Count
64
Registration Number
NCT05332028
Locations
🇹🇷

Mehmet Aksoy, Erzurum, string:Turkey, Turkey

Intrathecal Pethidine Plus Dexamethasone for Distal Lower Orthopedic Surgeries

First Posted Date
2022-03-31
Last Posted Date
2024-07-30
Lead Sponsor
Zagazig University
Target Recruit Count
46
Registration Number
NCT05303311
Locations
🇪🇬

Faculty of Medicine , Zagazig University, Zagazig, Sharkia, Egypt

Pain Control for Undergoing Costal Cartilage Harvesting

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2022-03-17
Last Posted Date
2024-10-02
Lead Sponsor
Mayo Clinic
Target Recruit Count
60
Registration Number
NCT05285566
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Cryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant Patients

First Posted Date
2022-03-11
Last Posted Date
2023-03-24
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
75
Registration Number
NCT05276258
Locations
🇺🇸

Houston Methodist Research Institute, Houston, Texas, United States

Comparison Between Different Anaesthesia Techniques Protecting Renal Function in Children Undergoing Radicle Nephrectomy

First Posted Date
2022-03-09
Last Posted Date
2022-03-09
Lead Sponsor
Alexandria University
Target Recruit Count
75
Registration Number
NCT05271253
Locations
🇪🇬

Haasan Elhoshy, Alexandria, Egypt

Comparison of Pain ReliefofBupivacaineWith Dexmedetomidine and Bupivacaine Alone in TransversusAbdominisPlane Block For Postoperative Anelgesia in Patients Undergoing Abdominal Surgeries

First Posted Date
2022-02-17
Last Posted Date
2022-03-07
Lead Sponsor
Sheikh Zayed Medical College
Target Recruit Count
80
Registration Number
NCT05244252
Locations
🇵🇰

Alina Zafar, Rahim Yar Khan, Punjab, Pakistan

Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy

First Posted Date
2022-02-04
Last Posted Date
2023-07-18
Lead Sponsor
Hartford Hospital
Target Recruit Count
114
Registration Number
NCT05224089
Locations
🇺🇸

Hartford Hospital, Hartford, Connecticut, United States

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