Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...
- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-08-16
- Last Posted Date
- 2023-01-18
- Lead Sponsor
- Mersin University
- Target Recruit Count
- 200
- Registration Number
- NCT05502146
- Locations
- 🇹🇷
Mersin University, Mersin, Yenişehir, Turkey
Transcutaneous Pulsed Radiofrequency in Migraine
Not Applicable
Active, not recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-08-12
- Last Posted Date
- 2023-02-03
- Lead Sponsor
- Diskapi Teaching and Research Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT05499689
- Locations
- 🇹🇷
Diskapi Yildirim Beyazıt Teaching and Research Hospital, Ankara, Altındğ, Turkey
Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery: A Randomized Controlled Trial
- First Posted Date
- 2022-08-10
- Last Posted Date
- 2022-08-10
- Lead Sponsor
- St. Luke's Hospital, Pennsylvania
- Target Recruit Count
- 300
- Registration Number
- NCT05494645
- Locations
- 🇺🇸
St. Luke's University Health Network, Bethlehem, Pennsylvania, United States
Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers
Phase 1
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-07-13
- Last Posted Date
- 2024-06-05
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 54
- Registration Number
- NCT05456490
- Locations
- 🇺🇸
Duke University, Durham, North Carolina, United States
Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks
- First Posted Date
- 2022-06-21
- Last Posted Date
- 2024-03-13
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 50
- Registration Number
- NCT05425979
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Erector Spinae Block for Spine Surgery
Phase 4
Terminated
- Conditions
- Interventions
- First Posted Date
- 2022-06-14
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 13
- Registration Number
- NCT05417113
- Locations
- 🇺🇸
Mount Sinai Hospital, New York, New York, United States
Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery
- First Posted Date
- 2022-06-10
- Last Posted Date
- 2022-06-10
- Lead Sponsor
- University of Puerto Rico
- Target Recruit Count
- 100
- Registration Number
- NCT05413902
- Locations
- 🇵🇷
Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico
Dose and Concentration Relationship for PENG Block in Hip Surgery
- First Posted Date
- 2022-06-01
- Last Posted Date
- 2024-02-07
- Target Recruit Count
- 112
- Registration Number
- NCT05400148
- Locations
- 🇹🇷
Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey
Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder
- First Posted Date
- 2022-05-26
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 127
- Registration Number
- NCT05391971
- Locations
- 🇺🇸
NYU Langone Health, New York, New York, United States
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-05-04
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- University of Chile
- Target Recruit Count
- 20
- Registration Number
- NCT05359731
- Locations
- 🇨🇱
Hospital Clínico Universidad de Chile, Santiago, Metropolitan, Chile
Drug Development Updates
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