Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy

Bupivacaine Versus Bupivacaine Plus Lidocaine in Infraclavicular Block

First Posted Date
2023-04-27
Last Posted Date
2024-01-17
Lead Sponsor
Hospital de San Carlos Dr. Benicio Arzola Medina
Target Recruit Count
40
Registration Number
NCT05834023
Locations
🇨🇱

Hospital de San Carlos Dr. Benicio Arzola Medina, San Carlos, Ñuble, Chile

Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-03-29
Last Posted Date
2023-08-22
Lead Sponsor
Assiut University
Target Recruit Count
86
Registration Number
NCT05790044

Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-03-27
Last Posted Date
2024-02-06
Lead Sponsor
Mansoura University
Target Recruit Count
58
Registration Number
NCT05785377
Locations
🇪🇬

Mansoura University-Emergency hospital-ICU, El Mansoura, Mansoura, Egypt

Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-03-02
Last Posted Date
2023-03-02
Lead Sponsor
Sohag University
Target Recruit Count
42
Registration Number
NCT05751291
Locations
🇪🇬

Sohag University Hospital, Sohag, Egypt

Steroids in Occipital Nerve Block for Treatment of Headache

First Posted Date
2023-02-17
Last Posted Date
2024-03-21
Lead Sponsor
Mayo Clinic
Target Recruit Count
120
Registration Number
NCT05732532
Locations
🇺🇸

Mayo Clinic Minnesota, Rochester, Minnesota, United States

Dexmedetomedine and Ketamine in Erector Spinae Block for Postoperative Analgesia Following Mastectomy.

First Posted Date
2023-02-14
Last Posted Date
2023-06-08
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
75
Registration Number
NCT05727098
Locations
🇪🇬

Hanafy, Cairo, Egypt

Sphenopalatine Ganglion Block Study

First Posted Date
2023-02-01
Last Posted Date
2024-10-08
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
220
Registration Number
NCT05707754
Locations
🇺🇸

Montefiore Medical Center, Bronx, New York, United States

Erector Spinae Plane Block and Ankle and Foot Surgery

First Posted Date
2023-02-01
Last Posted Date
2023-10-04
Lead Sponsor
Fayoum University Hospital
Target Recruit Count
68
Registration Number
NCT05708742
Locations
🇪🇬

Fayoum University hospital, Madīnat al Fayyūm, Faiyum Governorate, Egypt

The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain

Early Phase 1
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-01-18
Last Posted Date
2023-01-18
Lead Sponsor
Tanta University
Target Recruit Count
90
Registration Number
NCT05687981

Pain Control After Arthroscopic Shoulder Surgeries

First Posted Date
2023-01-17
Last Posted Date
2024-12-19
Lead Sponsor
Tanta University
Target Recruit Count
90
Registration Number
NCT05686395
Locations
🇪🇬

Faculty of Medicine Tanta University, Tanta, Egypt

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