Ilaprazole

Generic Name: Ilaprazole

Drug Type: Small Molecule

Chemical Formula: C_₁₉H_₁₈N_₄O_₂S

CAS Number: 172152-36-2

Unique Ingredient Identifier: 776Q6XX45J

Background: Ilaprazole has been investigated in Helicobacter Infections.

Indication: 用于治疗十二指肠溃疡及反流性食管炎。

Clinical Trials

The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers

Phase 4

Completed

Conditions: Duodenal Ulcer Due to Helicobacter Pylori

Interventions: Drug: Doxycycline Hyclate Enteric-Coated Capsules
Drug: Amoxicillin Capsules
Drug: Ilaprazole Enteric-Coated Tablets
Drug: Furazolidone Tablets
Drug: Potassium Citrate Tablets

First Posted Date: 2017-11-17

Last Posted Date: 2022-03-02

Lead Sponsor: The Third Xiangya Hospital of Central South University

Target Recruit Count: 184

Registration Number: NCT03342456

Locations: 🇨🇳
Shaoyang Central Hospital, Shaoyang, Hunan, China
🇨🇳
Xiangya Hospital of Central South University, Changsha, Hunan, China
🇨🇳
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China

and more 4 locations

Antimicrobial Susceptibility Testing Guided Triple Therapy in Salvage Helicobacter Pylori Treatment

Phase 4

Conditions: Antimicrobial Susceptibility Testing
Triple Therapy

Interventions: Drug: amoxicillin
Drug: tinidazole
Drug: clarithromycin
Drug: levofloxacin
Drug: furazolidone
Drug: tetracycline
Drug: Ilaprazole

First Posted Date: 2017-05-03

Last Posted Date: 2017-05-03

Lead Sponsor: Yanqing Li

Target Recruit Count: 120

Registration Number: NCT03139253

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Clarithromycin, Amoxicillin and Ilaprazole

Phase 1

Completed

Conditions: Drug Interaction Potentiation

Interventions: Drug: Clarithromycin 500mg
Drug: Ilaprazole 10mg
Drug: Amoxicillin 500 Mg

First Posted Date: 2016-12-20

Last Posted Date: 2017-01-26

Lead Sponsor: Il-Yang Pharm. Co., Ltd.

Target Recruit Count: 28

Registration Number: NCT02998437

Locations: 🇰🇷
Severance Hospital, Seoul, Korea, Republic of

Efficacy and Safety of 1-week Triple Therapy With Ilaprazole for the Eradication of Helicobacter Pylori

Phase 4

Completed

Conditions: Helicobacter Pylori Eradication

Interventions: Drug: Esoprazole
Drug: Ilaprazole

First Posted Date: 2016-08-19

Last Posted Date: 2016-08-19

Lead Sponsor: Livzon Pharmaceutical Group Inc.

Registration Number: NCT02873065

Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients

Phase 2

Completed

Conditions: Duodenal Ulcer

Interventions: Drug: 10 mg ilaprazole
Drug: 5 mg ilaprazole
Drug: 10 mg Rabeprazole

First Posted Date: 2016-07-28

Last Posted Date: 2016-07-28

Lead Sponsor: Livzon Pharmaceutical Group Inc.

Target Recruit Count: 408

Registration Number: NCT02847455

Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection

Phase 4

Completed

Conditions: Helicobacter Pylori Eradication Antibiotic

Interventions: Drug: Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy
Drug: Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy

First Posted Date: 2016-07-18

Last Posted Date: 2016-07-18

Lead Sponsor: Livzon Pharmaceutical Group Inc.

Target Recruit Count: 100

Registration Number: NCT02835560

The Prospective Study on the Effect of Ilaprazole in Non-erosive Reflux Disease Patients; Focused on Histologic Findings and Inflammatory Biomarker

Phase 4

Completed

Conditions: Gastrointestinal Subepithelial Tumors

Interventions: Drug: Ilaprazole

First Posted Date: 2016-01-28

Last Posted Date: 2019-03-22

Lead Sponsor: Yonsei University

Target Recruit Count: 20

Registration Number: NCT02666976

Locations: 🇰🇷
Severance Hospital, Seoul, Korea, Republic of

The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients

Phase 4

Completed

Conditions: Peptic Ulcer

Interventions: Drug: Ilaprazole
Drug: Amoxicillin
Drug: Metronidazole
Drug: Clarithromycin

First Posted Date: 2016-01-07

Last Posted Date: 2018-08-09

Lead Sponsor: Kyungpook National University Hospital

Target Recruit Count: 50

Registration Number: NCT02648659

Effects of Ilaprazole on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone ESD.

Phase 4

Completed

Conditions: Gastric Cancer

Interventions: Drug: Rabeprazole
Drug: Ilaprazole

First Posted Date: 2015-12-23

Last Posted Date: 2020-07-31

Lead Sponsor: Il-Yang Pharm. Co., Ltd.

Target Recruit Count: 176

Registration Number: NCT02638584

Locations: 🇰🇷
HALLYM UNIVERSITY MEDICAL CENTER, Chuncheon Sacred Heart Hospital, Chuncheon, Gangwon-do, Korea, Republic of

Dual Therapy With High Doses of Ilaprazole and Amoxicillin for Helicobacter Pylori Infection

Phase 4

Completed

Conditions: Helicobacter Infections

Interventions: Drug: Ilaprazole + Amoxicillin

First Posted Date: 2015-03-27

Last Posted Date: 2015-11-03

Lead Sponsor: Il-Yang Pharm. Co., Ltd.

Target Recruit Count: 90

Registration Number: NCT02401477

Locations: 🇰🇷
Dongguk University Ilsan Hospital, Goyang-si, Gyeonggi-do, Korea, Republic of

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