Nefopam
- Generic Name
- Nefopam
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO
- CAS Number
- 13669-70-0
- Unique Ingredient Identifier
- 4UP8060B7J
- Background
Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
- Indication
用于术后镇痛、癌痛、急性外伤痛。亦可用于急性胃炎、胆道蛔虫症、输尿管结石等内脏平滑肌收缩绞痛；局部麻醉、针麻等麻醉辅助用药。
- Associated Conditions
- Pain
Effectiveness of Nefopam in Breast Cancer Surgery
- Conditions
- Breast Neoplasm Malignant Primary
- Interventions
- Drug: Normal Saline
- First Posted Date
- 2016-10-31
- Last Posted Date
- 2018-01-11
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 88
- Registration Number
- NCT02949310
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of
Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia
- First Posted Date
- 2015-11-04
- Last Posted Date
- 2015-11-05
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 73
- Registration Number
- NCT02596269
Combination Effect of Nefopam With Propacetamol for Postoperative Pain After Thyroidectomy
- First Posted Date
- 2015-10-16
- Last Posted Date
- 2019-03-21
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 84
- Registration Number
- NCT02577068
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of
The Preemptive Analgesic Efficacy of Nefopam
- First Posted Date
- 2015-09-28
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 94
- Registration Number
- NCT02561468
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of
Postoperative Analgesic Effect of Nefopam
- First Posted Date
- 2015-09-28
- Last Posted Date
- 2016-10-28
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 78
- Registration Number
- NCT02561494
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of
Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia
- First Posted Date
- 2015-07-09
- Last Posted Date
- 2015-09-02
- Lead Sponsor
- Hallym University Kangnam Sacred Heart Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02493231
- Locations
- 🇰🇷
Hallym University Kangnam Sacred Heart Hospita, Seoul, Korea, Republic of
Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering
- Conditions
- Post Anaesthetic Shivering
- Interventions
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Lagos State Health Service Commission
- Target Recruit Count
- 130
- Registration Number
- NCT02441673
Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.
- Conditions
- Post Operative Analgesia
- Interventions
- First Posted Date
- 2013-06-20
- Last Posted Date
- 2018-02-06
- Lead Sponsor
- Rennes University Hospital
- Target Recruit Count
- 223
- Registration Number
- NCT01882530
- Locations
- 🇫🇷
Marcel Chauvin, Boulogne, France
🇫🇷Xavier Capdevila, Montpellier, France
🇫🇷Hawa Keita-Meyer, Colombes, France
The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
- Conditions
- Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
- Interventions
- First Posted Date
- 2013-03-08
- Last Posted Date
- 2014-02-19
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 54
- Registration Number
- NCT01808014
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Effect of Nefopam on Remifentanil Induced Postoperative Hyperalgesia
- Conditions
- Patients Undergoing Laparoscopic Gastrectomy
- Interventions
- First Posted Date
- 2012-11-26
- Last Posted Date
- 2014-02-19
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 25
- Registration Number
- NCT01732666
- Locations
- 🇰🇷
Severance hospital, Seoul, Korea, Republic of
Drug Development Updates
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