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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma

Phase 2

Completed

Conditions: Sarcoma

Interventions: Drug: cytarabine

First Posted Date: 2007-05-07

Last Posted Date: 2014-10-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 10

Registration Number: NCT00470275

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 70 locations

Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors

Phase 2

Completed

Conditions: Childhood Extracranial Germ Cell Tumor
Childhood Malignant Ovarian Germ Cell Tumor
Childhood Malignant Testicular Germ Cell Tumor
Ovarian Yolk Sac Tumor
Recurrent Childhood Malignant Germ Cell Tumor
Testicular Mixed Choriocarcinoma and Yolk Sac Tumor
Ovarian Embryonal Carcinoma
Recurrent Malignant Testicular Germ Cell Tumor
Ovarian Choriocarcinoma
Recurrent Ovarian Germ Cell Tumor

Interventions: Drug: Carboplatin
Biological: Filgrastim
Drug: Ifosfamide
Other: Laboratory Biomarker Analysis
Drug: Paclitaxel

First Posted Date: 2007-04-27

Last Posted Date: 2018-08-29

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 20

Registration Number: NCT00467051

Locations: 🇺🇸
The University of Arizona Medical Center-University Campus, Tucson, Arizona, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Kaiser Permanente Downey Medical Center, Downey, California, United States

and more 92 locations

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Phase 1

Withdrawn

Conditions: Brain and Central Nervous System Tumors
Unspecified Childhood Solid Tumor, Protocol Specific
Leukemia
Lymphoma

First Posted Date: 2007-04-11

Last Posted Date: 2014-08-08

Lead Sponsor: Children's Oncology Group

Registration Number: NCT00458744

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

Completed

Conditions: Ototoxicity
Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Procedure: management of therapy complications

First Posted Date: 2007-04-11

Last Posted Date: 2017-03-13

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 301

Registration Number: NCT00458887

Locations: 🇺🇸
UAB Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

and more 78 locations

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

Phase 3

Completed

Conditions: Childhood Myelodysplastic Syndromes
Childhood Acute Lymphoblastic Leukemia in Remission
Childhood Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia
de Novo Myelodysplastic Syndromes
Previously Treated Myelodysplastic Syndromes
Childhood Acute Myeloid Leukemia in Remission
Juvenile Myelomonocytic Leukemia
Recurrent Childhood Acute Lymphoblastic Leukemia
Secondary Myelodysplastic Syndromes

Interventions: Procedure: allogeneic bone marrow transplantation
Other: laboratory biomarker analysis
Biological: filgrastim

First Posted Date: 2007-03-22

Last Posted Date: 2022-04-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 27

Registration Number: NCT00450450

Locations: 🇺🇸
Children's Oncology Group, Arcadia, California, United States
🇺🇸
University of California San Francisco Medical Center-Parnassus, San Francisco, California, United States
🇺🇸
Children's Hospital Colorado, Aurora, Colorado, United States

and more 18 locations

Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging

Completed

Conditions: Localized Resectable Neuroblastoma
Precancerous Condition
Adrenocortical Carcinoma

Interventions: Procedure: computed tomography
Procedure: 3-Tesla magnetic resonance imaging
Procedure: Abdominal Sonogram

First Posted Date: 2007-03-09

Last Posted Date: 2017-02-09

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 97

Registration Number: NCT00445718

Locations: 🇺🇸
University of Arizona Health Sciences Center, Tucson, Arizona, United States
🇺🇸
Southern California Permanente Medical Group, Downey, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

and more 42 locations

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Completed

Conditions: Recurrent Neuroblastoma
Localized Unresectable Neuroblastoma
Regional Neuroblastoma
Stage 4 Neuroblastoma
Localized Resectable Neuroblastoma

Interventions: Other: Laboratory Biomarker Analysis

First Posted Date: 2007-02-19

Last Posted Date: 2018-08-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 9350

Registration Number: NCT00436696

Locations: 🇺🇸
University of Mississippi Medical Center, Jackson, Mississippi, United States
🇺🇸
Childrens Oncology Group, Philadelphia, Pennsylvania, United States

ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment

Phase 2

Completed

Conditions: Disseminated Neuroblastoma
Recurrent Neuroblastoma

Interventions: Drug: ABT-751
Procedure: quality-of-life assessment

First Posted Date: 2007-02-19

Last Posted Date: 2019-07-17

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 92

Registration Number: NCT00436852

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 9 locations

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Completed

Conditions: Childhood T Acute Lymphoblastic Leukemia
Cognitive Side Effects of Cancer Therapy
Long-Term Effects Secondary to Cancer Therapy in Children
Psychological Impact of Cancer
Untreated Childhood Acute Lymphoblastic Leukemia
Childhood B Acute Lymphoblastic Leukemia
Neurotoxicity Syndrome

Interventions: Procedure: Cognitive Assessment
Procedure: Diffusion Tensor Imaging
Other: Laboratory Biomarker Analysis
Other: Pharmacological Study
Procedure: Psychosocial Assessment and Care

First Posted Date: 2007-02-19

Last Posted Date: 2017-07-21

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 233

Registration Number: NCT00437060

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Southern California Permanente Medical Group, Downey, California, United States

and more 108 locations

Registration and Informed Consent Study for the Childhood Cancer Research Network

Not Applicable

Completed

Conditions: Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Procedure: educational intervention
Procedure: cancer prevention intervention

First Posted Date: 2007-02-12

Last Posted Date: 2013-06-27

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 2242

Registration Number: NCT00433394

Locations: 🇺🇸
Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California, United States
🇺🇸
Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center, Farmington, Connecticut, United States
🇺🇸
Lee Cancer Care of Lee Memorial Health System, Fort Myers, Florida, United States

and more 18 locations

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