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Children's Oncology Group

πŸ‡ΊπŸ‡ΈUnited States
Ownership
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Employees
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Market Cap
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Website

Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

Phase 3
Completed
Conditions
Childhood Atypical Teratoid/Rhabdoid Tumor
Interventions
Radiation: 3-Dimensional Conformal Radiation Therapy
Procedure: Autologous Hematopoietic Stem Cell Transplantation
Biological: Filgrastim
Other: Laboratory Biomarker Analysis
First Posted Date
2008-04-04
Last Posted Date
2024-04-23
Lead Sponsor
Children's Oncology Group
Target Recruit Count
70
Registration Number
NCT00653068
Locations
πŸ‡ΊπŸ‡Έ

Children's Hospital of Alabama, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 91 locations

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Not Applicable
Completed
Conditions
Ewing Sarcoma of Bone
Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions
First Posted Date
2008-02-20
Last Posted Date
2014-09-25
Lead Sponsor
Children's Oncology Group
Target Recruit Count
35
Registration Number
NCT00618813
Locations
πŸ‡ΊπŸ‡Έ

Children's Oncology Group, Monrovia, California, United States

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Phase 3
Completed
Conditions
Localized Resectable Neuroblastoma
Localized Unresectable Neuroblastoma
Recurrent Neuroblastoma
Regional Neuroblastoma
Stage 4 Neuroblastoma
Stage 4S Neuroblastoma
Interventions
Procedure: Autologous Hematopoietic Stem Cell Transplantation
Radiation: External Beam Radiation Therapy
Biological: Filgrastim
Other: Laboratory Biomarker Analysis
Procedure: Peripheral Blood Stem Cell Transplantation
Other: Pharmacological Study
First Posted Date
2007-12-05
Last Posted Date
2022-04-28
Lead Sponsor
Children's Oncology Group
Target Recruit Count
665
Registration Number
NCT00567567
Locations
πŸ‡ΊπŸ‡Έ

Children's Hospital of Alabama, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

USA Health Strada Patient Care Center, Mobile, Alabama, United States

and more 187 locations

Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 3
Completed
Conditions
Acute Undifferentiated Leukemia
Acute Lymphoblastic Leukemia
Childhood T Acute Lymphoblastic Leukemia
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Biopsy
Procedure: Echocardiography
Biological: Filgrastim
Other: Laboratory Biomarker Analysis
Procedure: Multigated Acquisition Scan
Other: Pharmacological Study
First Posted Date
2007-11-12
Last Posted Date
2024-07-15
Lead Sponsor
Children's Oncology Group
Target Recruit Count
218
Registration Number
NCT00557193
Locations
πŸ‡ΊπŸ‡Έ

Children's Hospital of Alabama, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

Phoenix Childrens Hospital, Phoenix, Arizona, United States

and more 167 locations

Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma

Phase 3
Completed
Conditions
Extraocular Retinoblastoma
Interventions
Procedure: Autologous Bone Marrow Transplantation
Procedure: Autologous Hematopoietic Stem Cell Transplantation
Procedure: In Vitro-Treated Peripheral Blood Stem Cell Transplantation
Radiation: Radiation Therapy
First Posted Date
2007-11-07
Last Posted Date
2025-01-13
Lead Sponsor
Children's Oncology Group
Target Recruit Count
60
Registration Number
NCT00554788
Locations
πŸ‡ΊπŸ‡Έ

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia, United States

πŸ‡ΊπŸ‡Έ

Children's Hospital of Alabama, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

and more 70 locations

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Phase 2
Completed
Conditions
Leukemia
Interventions
Biological: anti-thymocyte globulin
Other: laboratory biomarker analysis
Other: pharmacological study
Procedure: allogeneic bone marrow transplantation
Procedure: allogeneic hematopoietic stem cell transplantation
First Posted Date
2007-11-04
Last Posted Date
2020-04-16
Lead Sponsor
Children's Oncology Group
Target Recruit Count
158
Registration Number
NCT00553202
Locations
πŸ‡ΊπŸ‡Έ

UAB Comprehensive Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

Phoenix Children's Hospital, Phoenix, Arizona, United States

πŸ‡ΊπŸ‡Έ

Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California, United States

and more 49 locations

Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia

Not Applicable
Completed
Conditions
Adult Acute Lymphoblastic Leukemia
Childhood Acute Lymphoblastic Leukemia
Interventions
Other: Laboratory Biomarker Analysis
Other: Pharmacological Study
First Posted Date
2007-09-28
Last Posted Date
2019-07-09
Lead Sponsor
Children's Oncology Group
Target Recruit Count
59
Registration Number
NCT00537030
Locations
πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

Phoenix Childrens Hospital, Phoenix, Arizona, United States

πŸ‡ΊπŸ‡Έ

Kaiser Permanente Downey Medical Center, Downey, California, United States

and more 40 locations

Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma

First Posted Date
2007-07-11
Last Posted Date
2021-07-06
Lead Sponsor
Children's Oncology Group
Target Recruit Count
464
Registration Number
NCT00499616
Locations
πŸ‡ΊπŸ‡Έ

UAB Comprehensive Cancer Center, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States

πŸ‡ΊπŸ‡Έ

Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 186 locations

Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Completed
Conditions
Untreated Childhood Acute Lymphoblastic Leukemia
Untreated Adult Acute Lymphoblastic Leukemia
Interventions
Other: laboratory biomarker analysis
First Posted Date
2007-06-05
Last Posted Date
2023-08-03
Lead Sponsor
Children's Oncology Group
Target Recruit Count
11196
Registration Number
NCT00482352
Locations
πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of South Alabama, Mobile, Alabama, United States

πŸ‡ΊπŸ‡Έ

Phoenix Childrens Hospital, Phoenix, Arizona, United States

and more 197 locations

Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia

Phase 1
Completed
Conditions
Leukemia
Interventions
First Posted Date
2007-05-07
Last Posted Date
2017-03-15
Lead Sponsor
Children's Oncology Group
Target Recruit Count
14
Registration Number
NCT00469859
Locations
πŸ‡ΊπŸ‡Έ

Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

Children's Hospital of Orange County, Orange, California, United States

πŸ‡ΊπŸ‡Έ

Children's National Medical Center, Washington, District of Columbia, United States

and more 18 locations
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