Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell Transplant
- Conditions
- Interventions
- First Posted Date
- 2008-08-06
- Last Posted Date
- 2018-08-07
- Lead Sponsor
- Children's Oncology Group
- Registration Number
- NCT00728585
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
- First Posted Date
- 2008-07-16
- Last Posted Date
- 2023-11-09
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 131
- Registration Number
- NCT00716976
- Locations
- 🇺🇸
University of Illinois Cancer Center, Chicago, Illinois, United States
🇺🇸University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami, Florida, United States
🇺🇸Rady Children's Hospital - San Diego, San Diego, California, United States
Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers
- First Posted Date
- 2008-06-04
- Last Posted Date
- 2019-10-08
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 234
- Registration Number
- NCT00690469
- Locations
- 🇺🇸
Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States
🇺🇸University of Missouri - Ellis Fischel, Columbia, Missouri, United States
Evaluating Dactinomycin and Vincristine in Young Patients With Cancer
- Conditions
- Interventions
- First Posted Date
- 2008-05-07
- Last Posted Date
- 2017-05-17
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 158
- Registration Number
- NCT00674193
- Locations
- 🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Rainbow Babies and Childrens Hospital, Cleveland, Ohio, United States
🇺🇸Cleveland Clinic Foundation, Cleveland, Ohio, United States
Pharmacokinetics of Daunorubicin in Young Patients With Cancer
- Conditions
- Interventions
- First Posted Date
- 2008-05-07
- Last Posted Date
- 2020-04-14
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 107
- Registration Number
- NCT00673257
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
🇺🇸Childrens Hospital Los Angeles, Los Angeles, California, United States
🇺🇸Winship Cancer Institute of Emory University, Atlanta, Georgia, United States
Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
- Conditions
- Interventions
- Drug: Calaspargase Pegol-mknlDrug: CyclophosphamideDrug: CytarabineDrug: Daunorubicin HydrochlorideDrug: DexamethasoneDrug: Doxorubicin HydrochlorideOther: Laboratory Biomarker AnalysisDrug: MercaptopurineDrug: MethotrexateDrug: PegaspargaseOther: Pharmacological StudyDrug: PrednisoneRadiation: Radiation TherapyDrug: ThioguanineDrug: Vincristine Sulfate
- First Posted Date
- 2008-05-02
- Last Posted Date
- 2021-04-27
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 166
- Registration Number
- NCT00671034
- Locations
- 🇺🇸
Connecticut Children's Medical Center, Hartford, Connecticut, United States
🇺🇸University of Connecticut, Farmington, Connecticut, United States
🇺🇸University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System
- Conditions
- Interventions
- Radiation: 3-Dimensional Conformal Radiation TherapyProcedure: Autologous Hematopoietic Stem Cell TransplantationDrug: CarboplatinDrug: CisplatinDrug: CyclophosphamideDrug: EtoposideBiological: FilgrastimOther: Laboratory Biomarker AnalysisDrug: Leucovorin CalciumDrug: MethotrexateDrug: ThiotepaDrug: Vincristine Sulfate
- First Posted Date
- 2008-04-04
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 70
- Registration Number
- NCT00653068
- Locations
- 🇺🇸
Prisma Health Richland Hospital, Columbia, South Carolina, United States
🇺🇸Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸Lee Memorial Health System, Fort Myers, Florida, United States
Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors
- Conditions
- Interventions
- First Posted Date
- 2008-02-20
- Last Posted Date
- 2014-09-25
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 35
- Registration Number
- NCT00618813
- Locations
- 🇺🇸
Children's Oncology Group, Monrovia, California, United States
Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma
- Conditions
- Interventions
- Procedure: Autologous Hematopoietic Stem Cell TransplantationDrug: CarboplatinDrug: CisplatinDrug: CyclophosphamideDrug: Doxorubicin HydrochlorideDrug: EtoposideRadiation: External Beam Radiation TherapyBiological: FilgrastimDrug: IsotretinoinOther: Laboratory Biomarker AnalysisDrug: MelphalanProcedure: Peripheral Blood Stem Cell TransplantationOther: Pharmacological StudyDrug: Topotecan HydrochlorideDrug: ThiotepaDrug: Vincristine Sulfate Liposome
- First Posted Date
- 2007-12-05
- Last Posted Date
- 2022-04-28
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 665
- Registration Number
- NCT00567567
- Locations
- 🇺🇸
Cedars Sinai Medical Center, Los Angeles, California, United States
🇺🇸Valley Children's Hospital, Madera, California, United States
🇺🇸Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
- Conditions
- Interventions
- Drug: AsparaginaseProcedure: Biospecimen CollectionProcedure: Bone Marrow BiopsyDrug: CyclophosphamideDrug: CytarabineDrug: Daunorubicin HydrochlorideDrug: DexamethasoneProcedure: EchocardiographyDrug: EtoposideBiological: FilgrastimOther: Laboratory Biomarker AnalysisDrug: Leucovorin CalciumDrug: LestaurtinibDrug: MercaptopurineDrug: MethotrexateDrug: MethylprednisoloneProcedure: Multigated Acquisition ScanDrug: PegaspargaseOther: Pharmacological StudyDrug: PrednisoneDrug: Therapeutic HydrocortisoneDrug: Vincristine Sulfate
- First Posted Date
- 2007-11-12
- Last Posted Date
- 2024-07-15
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 218
- Registration Number
- NCT00557193
- Locations
- 🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
🇺🇸Connecticut Children's Medical Center, Hartford, Connecticut, United States
🇺🇸MedStar Georgetown University Hospital, Washington, District of Columbia, United States