Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients
- First Posted Date
- 2015-03-20
- Last Posted Date
- 2019-08-15
- Lead Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
- Registration Number
- NCT02394418
SEP Changes During Deep Anesthesia
- Conditions
- Somatosensory Evoked Potentials, and Electroencephalography
- Interventions
- First Posted Date
- 2015-03-20
- Last Posted Date
- 2015-03-20
- Lead Sponsor
- Andrea Szelenyi
- Target Recruit Count
- 60
- Registration Number
- NCT02394002
- Locations
- 🇩🇪
Neurosurgical Clinic, Duesseldorf, Germany
Does Repetitive Electroconvulsive Therapies Affect Propofol Induction Dose ?
- First Posted Date
- 2015-03-20
- Last Posted Date
- 2015-03-20
- Lead Sponsor
- Ankara University
- Target Recruit Count
- 10
- Registration Number
- NCT02394847
Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery
- Conditions
- SurgeryDisorder; Mental, SedativePain, Postoperative
- Interventions
- First Posted Date
- 2015-03-19
- Last Posted Date
- 2015-08-05
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02393066
- Locations
- 🇨🇳
National Taiwan University Hospital, Taipei, Taiwan
Determine the ED50 of Dexmedetomidine to Facilitate LMA Insertion During Anaesthesia Induction
- First Posted Date
- 2015-03-12
- Last Posted Date
- 2015-03-12
- Lead Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
- Target Recruit Count
- 30
- Registration Number
- NCT02386462
- Locations
- 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China
Remifentanil for the I-gel and Laryngeal Mask Airway Insertion
- Conditions
- Supraglottic Airways for General Anesthesia
- Interventions
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2015-10-14
- Lead Sponsor
- Ajou University School of Medicine
- Target Recruit Count
- 41
- Registration Number
- NCT02382354
- Locations
- 🇰🇷
Ajou University hospital, Suwon, Korea, Republic of
Comparative Effect of Theipoental and Propofol in IVF Outcome
- First Posted Date
- 2015-03-04
- Last Posted Date
- 2015-03-04
- Lead Sponsor
- Aristotle University Of Thessaloniki
- Target Recruit Count
- 180
- Registration Number
- NCT02377778
- Locations
- 🇬🇷
Unit for Human Reproduction, 1st Dept of OB/Gyn, Medical School, Aristotle UNiversity of Thessaloniki, Thessaloniki, Greece
Therapeutic Hypothermia With Propofol in Survival and Neurological Prognoses After Cardiac Arrest
- First Posted Date
- 2015-02-20
- Last Posted Date
- 2016-03-29
- Lead Sponsor
- Far Eastern Memorial Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT02367755
- Locations
- 🇨🇳
Far Eastern Memorial Hospital, New Taipei City, Taiwan
Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.
- First Posted Date
- 2015-02-19
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
- Registration Number
- NCT02366299
Pharmacokinetics and Pharmacodynamics of Rocuronium in Closed-Loop Infusion System
- Conditions
- TOFSex
- Interventions
- First Posted Date
- 2015-02-18
- Last Posted Date
- 2015-02-26
- Lead Sponsor
- Tianjin Medical University General Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT02364934
Drug Development Updates
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