MedPath

Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Clinical Trials
Related News

Postoperative Sedation After Cardiac Surgery

Not Applicable
Terminated
Conditions
Surgery, Cardiac
Anesthesia
Interventions
Device: Automated postoperative sedation
Drug: propofol
Drug: remifentanil
First Posted Date
2015-07-02
Last Posted Date
2017-05-17
Lead Sponsor
Hopital Foch
Target Recruit Count
19
Registration Number
NCT02488486
Locations
🇫🇷

Clinique Ambroise Paré, Neuilly-sur-Seine, Hauts-de-Seine, France

The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy

Phase 4
Completed
Conditions
Gastrointestinal Dysfunction
Alteration of Cognitive Function
Interventions
Drug: Midazolam
Drug: Remifentanil
Drug: Meperidine
Drug: Propofol
First Posted Date
2015-07-01
Last Posted Date
2020-09-03
Lead Sponsor
Ufuk University
Target Recruit Count
103
Registration Number
NCT02486328

Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients

Not Applicable
Completed
Conditions
Migraine Headache
Interventions
Drug: Propofol
First Posted Date
2015-06-30
Last Posted Date
2024-03-06
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
40
Registration Number
NCT02485418
Locations
🇺🇸

Children's Health Children's Medical Center Dallas, Dallas, Texas, United States

Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia

Phase 3
Conditions
Heart Diseases
Children
Anaesthesia
Magnetic Resonance Imaging
Interventions
Drug: Remifentanil and/or propofol
Drug: propofol
First Posted Date
2015-06-25
Last Posted Date
2019-01-10
Lead Sponsor
Alder Hey Children's NHS Foundation Trust
Target Recruit Count
35
Registration Number
NCT02481791
Locations
🇬🇧

Alder Hey Children's Hospital, Liverpool, Merseyside, United Kingdom

Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and Kyphoplasty

Not Applicable
Completed
Conditions
Fractures, Compression
Interventions
Drug: Remifentanil
Drug: Dexmedetomidine
Drug: midazolam
Drug: propofol
Drug: ephedrine
First Posted Date
2015-06-22
Last Posted Date
2015-06-24
Lead Sponsor
Hallym University Medical Center
Target Recruit Count
75
Registration Number
NCT02476981
Locations
🇰🇷

Hallym University Sacred Heart Hospital, Anyang-si, Dongan-gu, Korea, Republic of

Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block

Phase 4
Completed
Conditions
Shoulder Pain
Interventions
Drug: Dexmedetomidine
Drug: Propofol
Other: Interscalene block
First Posted Date
2015-06-12
Last Posted Date
2024-11-13
Lead Sponsor
Maimonides Medical Center
Target Recruit Count
50
Registration Number
NCT02469961
Locations
🇺🇸

Maimonides Medical Center, Brooklyn, New York, United States

The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy

First Posted Date
2015-06-10
Last Posted Date
2016-01-27
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
75
Registration Number
NCT02467595

Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery

First Posted Date
2015-06-08
Last Posted Date
2015-07-27
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
50
Registration Number
NCT02464722

Trial- Dysphagia From ETT or GI Endoscopy

Not Applicable
Withdrawn
Conditions
Respiratory Complications
Dysphagia
Interventions
Device: endotracheal tube
Drug: propofol
Drug: Fentanyl
Drug: Dexamethasone
Drug: Ondansetron
Drug: sevoflurane, nitrous oxide and oxygen
First Posted Date
2015-06-02
Last Posted Date
2020-03-09
Lead Sponsor
Baylor College of Medicine
Registration Number
NCT02460055

Effect of Anesthesia Technique on Outcome After Hip Fracture Surgery in Elderly Adult Patients

Not Applicable
Completed
Conditions
Hip Fracture
Interventions
Drug: Desflurane
Drug: Propofol
Drug: Bupivacaine
First Posted Date
2015-06-01
Last Posted Date
2019-03-19
Lead Sponsor
Yonsei University
Target Recruit Count
186
Registration Number
NCT02458547
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy