Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
- First Posted Date
- 2014-05-08
- Last Posted Date
- 2014-05-08
- Lead Sponsor
- Negovsky Reanimatology Research Institute
- Target Recruit Count
- 130
- Registration Number
- NCT02133638
- Locations
- 🇷🇺
Medical center of the Main Administration for Service to the Diplomatic Corps, Moscow, Russian Federation
Horner's SD After Thoracic Epidural Block
- Conditions
- Interventions
- First Posted Date
- 2014-05-05
- Last Posted Date
- 2014-05-05
- Lead Sponsor
- Soonchunhyang University Hospital
- Target Recruit Count
- 450
- Registration Number
- NCT02130739
- Locations
- 🇰🇷
Soonchunhyang University Seoul Hospital, Seoul, Korea, Republic of
Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in ICU.
- First Posted Date
- 2014-04-24
- Last Posted Date
- 2014-04-24
- Lead Sponsor
- Tianjin Third Central Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT02122055
Decreasing the Incidence of Delirium After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2014-04-22
- Last Posted Date
- 2018-06-12
- Lead Sponsor
- University of California, Los Angeles
- Registration Number
- NCT02119806
- Locations
- 🇺🇸
Ronald Reagan UCLA Medical Center, Department of Anesthesiology, Los Angeles, California, United States
A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients
- Conditions
- Interventions
- First Posted Date
- 2014-04-21
- Last Posted Date
- 2014-07-15
- Lead Sponsor
- Jiangsu Nhwa Pharmaceutical Co., Ltd.
- Target Recruit Count
- 1152
- Registration Number
- NCT02117401
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
- Conditions
- Interventions
- First Posted Date
- 2014-04-11
- Last Posted Date
- 2019-07-23
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 6
- Registration Number
- NCT02111447
- Locations
- 🇺🇸
Women and Chidren's Hospital Of Buffalo, Buffalo, New York, United States
The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis
- Conditions
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2019-03-04
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 12
- Registration Number
- NCT02109965
- Locations
- 🇨🇳
National Taiwan University Hospital, Taipei, Taiwan
The Effect of Induction Technique on Postoperative Pain and Agitation
- Conditions
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2015-03-13
- Lead Sponsor
- Mustafa Kemal University
- Target Recruit Count
- 2
- Registration Number
- NCT02110745
- Locations
- 🇹🇷
Mustafa Kemal University Medicine Faculty Anesthesiology Department, Hatay, Turkey
Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.
- First Posted Date
- 2014-04-08
- Last Posted Date
- 2018-06-12
- Lead Sponsor
- Tao Zhang
- Target Recruit Count
- 68
- Registration Number
- NCT02107170
- Locations
- 🇨🇳
First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China
Effects of Desflurane Versus Propofol on Hemostasis During Splenectomy
- First Posted Date
- 2014-03-05
- Last Posted Date
- 2017-10-11
- Lead Sponsor
- Theodor Bilharz Research Institute
- Target Recruit Count
- 30
- Registration Number
- NCT02079064
- Locations
- 🇪🇬
Theodor Bilharz Research Institute, Giza, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.