Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Comparison of Two Anaesthetics on Brain During Brain Tumour Surgery
- First Posted Date
- 2014-09-01
- Last Posted Date
- 2014-09-01
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 40
- Registration Number
- NCT02229201
- Locations
- 🇸🇮
University Medical Centre Ljubljana, Ljubljana, Slovenia
Noninvasive Ventilation Bundle in Postoperative Respiratory Failure
- Conditions
- Interventions
- First Posted Date
- 2014-08-12
- Last Posted Date
- 2015-08-18
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 158
- Registration Number
- NCT02214368
- Locations
- 🇨🇳
Department of Critical care medicine of West China Hospital, Chengdu, Sichuan, China
The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2014-08-11
- Last Posted Date
- 2014-08-11
- Lead Sponsor
- Huazhong University of Science and Technology
- Target Recruit Count
- 60
- Registration Number
- NCT02213718
- Locations
- 🇨🇳
Dept. of Anesthesiolgy, Tongji hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2014-08-05
- Last Posted Date
- 2014-08-05
- Target Recruit Count
- 150
- Registration Number
- NCT02208596
Prevention of Propofol Injection Pain
- First Posted Date
- 2014-07-29
- Last Posted Date
- 2014-09-25
- Lead Sponsor
- Yeditepe University Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT02203175
- Locations
- 🇹🇷
Yeditepe University Hospital, Istanbul, Devlet Yolu, Ankara cad 102/104, Kozyatagi, Turkey
Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure
- Conditions
- Interventions
- First Posted Date
- 2014-07-29
- Last Posted Date
- 2020-03-02
- Lead Sponsor
- Texas Tech University Health Sciences Center
- Target Recruit Count
- 36
- Registration Number
- NCT02203019
- Locations
- 🇺🇸
University Medical Center, Lubbock, Texas, United States
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2014-07-29
- Last Posted Date
- 2017-03-09
- Lead Sponsor
- University of Debrecen
- Target Recruit Count
- 25
- Registration Number
- NCT02203097
- Locations
- 🇭🇺
University of Debrecen Medical and Health Science Center Department of Anesthesiology and Intensive Care, Debrecen, Hungary
Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients
- First Posted Date
- 2014-07-28
- Last Posted Date
- 2014-07-28
- Lead Sponsor
- Zhujiang Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02202239
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
- First Posted Date
- 2014-07-22
- Last Posted Date
- 2019-03-14
- Lead Sponsor
- Chonnam National University Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT02197403
- Locations
- 🇰🇷
Chonnam National University Hwasun Hospital, Hwasun, Jeollanamdo, Korea, Republic of
Effect of Anesthetics on Oxygenation and Microcirculation During One-lung Ventilation
- Conditions
- Interventions
- First Posted Date
- 2014-07-16
- Last Posted Date
- 2016-10-13
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 104
- Registration Number
- NCT02191371
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Drug Development Updates
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