Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to Placebo
- First Posted Date
- 2021-05-14
- Last Posted Date
- 2021-05-14
- Lead Sponsor
- Universidad Nacional de Colombia
- Target Recruit Count
- 114
- Registration Number
- NCT04887649
- Locations
- 🇨🇴
Universidad Nacional; Maternal and Child Institute, Bogota, Colombia
A Trial of SHR0410 Injection for the Treatment of Pain After Endoscopic Surgery of the Lower Abdominal
- First Posted Date
- 2021-04-21
- Last Posted Date
- 2022-02-10
- Lead Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Target Recruit Count
- 228
- Registration Number
- NCT04852003
- Locations
- 🇨🇳
West China Hospital of Sichuan University, Chengdu, Sichuan, China
TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2021-04-01
- Last Posted Date
- 2022-02-24
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT04824274
- Locations
- 🇰🇷
Jin-Tae Kim, Seoul, Korea, Republic of
A Clinical Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery
- First Posted Date
- 2021-03-12
- Last Posted Date
- 2021-08-12
- Lead Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Target Recruit Count
- 192
- Registration Number
- NCT04794738
- Locations
- 🇨🇳
Shanghai Jiaotong University School of Medicine,Renji Hospital, Shanghai, Shanghai, China
Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)
- Conditions
- Interventions
- First Posted Date
- 2021-02-26
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 50
- Registration Number
- NCT04772222
- Locations
- 🇺🇸
McKay-Dee Hospital, Ogden, Utah, United States
🇺🇸Primary Children's Hospital, Salt Lake City, Utah, United States
🇺🇸University of Utah Health, Salt Lake City, Utah, United States
A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.
- First Posted Date
- 2021-02-23
- Last Posted Date
- 2022-07-06
- Lead Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Target Recruit Count
- 528
- Registration Number
- NCT04766463
- Locations
- 🇨🇳
Union Hospital Affiliated to Tongji Medical Collage Huazhong University of Science and Technology, Wuhan, Wuhan, China
Methadone for Spinal Fusion Surgery.
- Conditions
- Interventions
- First Posted Date
- 2021-02-21
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 114
- Registration Number
- NCT04764825
- Locations
- 🇩🇰
Aarhus University Hospital, Aarhus, Denmark
Comparison of Two Analgesic Strategies After Scheduled Caesarean
- Conditions
- Interventions
- First Posted Date
- 2021-02-16
- Last Posted Date
- 2024-08-05
- Target Recruit Count
- 104
- Registration Number
- NCT04755712
- Locations
- 🇫🇷
MAUPAIN, Quincy-sous-Sénart, France
Intrathecal Opioids for Colorectal Resection
- Conditions
- Interventions
- First Posted Date
- 2021-02-12
- Last Posted Date
- 2024-03-26
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 80
- Registration Number
- NCT04752033
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control
- First Posted Date
- 2021-01-07
- Last Posted Date
- 2021-01-07
- Lead Sponsor
- CHRISTUS Health
- Target Recruit Count
- 32
- Registration Number
- NCT04698772
- Locations
- 🇺🇸
CHRISTUS, Corpus Christi, Texas, United States
Drug Development Updates
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