Epinephrine
- Generic Name
- Epinephrine
- Brand Names
- Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13NO3
- CAS Number
- 51-43-4
- Unique Ingredient Identifier
- YKH834O4BH
- Background
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...
- Indication
Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...
- Associated Conditions
- Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
- Associated Therapies
- -
Study of Multistep Pharmacological and Invasive Management for Cardiogenic Shock
- First Posted Date
- 2015-10-30
- Last Posted Date
- 2021-07-26
- Lead Sponsor
- Niguarda Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT02591771
- Locations
- 🇮🇹
Niguarda Hospital, Milan, MI, Italy
🇮🇹Ospedale San Raffaele, Milano, Italy
Nebulized Adrenalin and Oral Betamethasone in Children With Bronchiolitis Attending Pediatric Emergencies.
- Conditions
- Interventions
- First Posted Date
- 2015-10-27
- Last Posted Date
- 2017-09-12
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 195
- Registration Number
- NCT02586961
- Locations
- 🇫🇷
AP-HP, Antoine Béclère Hospital, Clamart, France
Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-10-23
- Last Posted Date
- 2020-09-11
- Lead Sponsor
- St. Olavs Hospital
- Target Recruit Count
- 123
- Registration Number
- NCT02585011
- Locations
- 🇳🇴
Ortopedisk forskningssenter, St.Olavs Hospital, Trondheim, Norway
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-10-07
- Last Posted Date
- 2022-03-04
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 64
- Registration Number
- NCT02570503
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-09-07
- Last Posted Date
- 2019-10-18
- Lead Sponsor
- Kootenai Health
- Target Recruit Count
- 239
- Registration Number
- NCT02543801
Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
- First Posted Date
- 2015-09-03
- Last Posted Date
- 2016-11-15
- Lead Sponsor
- Lawson Health Research Institute
- Target Recruit Count
- 135
- Registration Number
- NCT02540070
- Locations
- 🇨🇦
University Hospital, London Health Sciences Centre, London, Ontario, Canada
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
- Conditions
- Interventions
- First Posted Date
- 2015-09-01
- Last Posted Date
- 2015-09-01
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT02537353
To Compare a Hemostatic Powder TC-325 and Standard Treatment in the Control of Acute Upper Gastrointestinal Bleeding From Nonvariceal Causes
- First Posted Date
- 2015-08-27
- Last Posted Date
- 2019-10-11
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 224
- Registration Number
- NCT02534571
- Locations
- 🇨🇳
Endoscopy Centre, Hong Kong, Hong Kong, China
Protracted Mixture of Local Anesthetics for Major Foot and Ankle Surgery
- Conditions
- Interventions
- First Posted Date
- 2015-08-18
- Last Posted Date
- 2016-09-23
- Lead Sponsor
- Rasmus Wulff Hauritz
- Target Recruit Count
- 56
- Registration Number
- NCT02526199
- Locations
- 🇩🇰
Department of Anesthesia, Aarhus University Hospital, Aarhus, Region Midt, Denmark
TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy
- Conditions
- Interventions
- First Posted Date
- 2015-08-10
- Last Posted Date
- 2019-02-08
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 87
- Registration Number
- NCT02519023
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Drug Development Updates
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