Epinephrine

Generic Name
Epinephrine
Brand Names
Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
Drug Type
Small Molecule
Chemical Formula
C9H13NO3
CAS Number
51-43-4
Unique Ingredient Identifier
YKH834O4BH
Background

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication

Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions
Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
Associated Therapies
-
Clinical Trials
Related News

Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis

First Posted Date
2016-07-21
Last Posted Date
2017-03-03
Lead Sponsor
Anhui Provincial Hospital
Target Recruit Count
670
Registration Number
NCT02839356
Locations
🇨🇳

Department of General Surgery, Anhui Provincial Hospital Affiliated with Anhui Medical University, He Fei, Anhui, China

4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis

First Posted Date
2016-06-21
Last Posted Date
2016-06-21
Lead Sponsor
Dr. D. Y. Patil Dental College & Hospital
Target Recruit Count
25
Registration Number
NCT02807298

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

First Posted Date
2016-06-08
Last Posted Date
2018-04-05
Lead Sponsor
University of Iowa
Target Recruit Count
102
Registration Number
NCT02793947
Locations
🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

First Posted Date
2016-04-15
Last Posted Date
2022-01-24
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
52
Registration Number
NCT02740127
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Desflurane
Drug: Isoflurane
Drug: Ephedrine
Drug: Phenylephrine
Drug: Norepinephrine
Drug: Epinephrine
Drug: Dobutamine
Drug: Dopamine
Drug: Isoproterenol
Drug: Milrinone
Drug: Atropine
Drug: Glycopyrrolate
Drug: Vasopressin
Drug: Terlipressin
Drug: Sodium Chloride 0.9%
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Fresh Frozen Plasma
Drug: Packed Red Blood Cells
Drug: Albumin solutions
Drug: Plasma-Lyte
Drug: Lidocaine
Drug: Bupivacaine
Drug: Levobupivacaine
Drug: Ropivacaine
Drug: Mepivacaine
Drug: Tetracaine
Drug: Prilocaine
Drug: Procaine
Drug: Chloroprocaine
Drug: Benzocaine
Drug: Articaine
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

The Prevention of Hypotension After Epidural Analgesia After Major Surgery

Not Applicable
Completed
Conditions
Hypotension
Pain
Interventions
Drug: Ropivacaine
Drug: Epinephrine
First Posted Date
2016-03-30
Last Posted Date
2024-07-25
Lead Sponsor
University of Florida
Target Recruit Count
66
Registration Number
NCT02722746
Locations
🇺🇸

UF Health, Gainesville, Florida, United States

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

First Posted Date
2016-03-08
Last Posted Date
2019-08-28
Lead Sponsor
NYU Langone Health
Target Recruit Count
66
Registration Number
NCT02701582
Locations
🇺🇸

New York University School of Medicine, New York, New York, United States

Dose Response of Epinephrine

Early Phase 1
Recruiting
Conditions
Diabetes Complications
Interventions
Other: Saline infusion
Drug: Epinephrine
First Posted Date
2016-02-26
Last Posted Date
2024-03-06
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
32
Registration Number
NCT02692313
Locations
🇺🇸

University of Maryland, Baltimore, Baltimore, Maryland, United States

Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration

Not Applicable
Completed
Conditions
Postoperative Pain
Interventions
Drug: Ropivacaine
Drug: Epinephrine
First Posted Date
2016-01-18
Last Posted Date
2018-11-29
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
60
Registration Number
NCT02658240
Locations
🇺🇸

UTSW Parkland Health Hospital System, Dallas, Texas, United States

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

First Posted Date
2016-01-18
Last Posted Date
2018-05-09
Lead Sponsor
William Beaumont Hospitals
Target Recruit Count
100
Registration Number
NCT02658149
Locations
🇺🇸

Beaumont Hospital, Royal Oak, Michigan, United States

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