Epinephrine

Generic Name
Epinephrine
Brand Names
Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
Drug Type
Small Molecule
Chemical Formula
C9H13NO3
CAS Number
51-43-4
Unique Ingredient Identifier
YKH834O4BH
Background

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication

Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions
Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
Associated Therapies
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Implementation of a Pain Management Protocol for Total Knee Arthroplasty

First Posted Date
2015-06-18
Last Posted Date
2019-01-18
Lead Sponsor
Health Sciences North Research Institute
Target Recruit Count
220
Registration Number
NCT02474654
Locations
🇨🇦

Health Sciences North Research Institute, Sudbury, Ontario, Canada

Systemic Steroids for Peripheral Nerve Blocks

First Posted Date
2015-06-08
Last Posted Date
2018-08-31
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
115
Registration Number
NCT02464176
Locations
🇺🇸

Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, United States

Perineural Steroids for Peripheral Nerve Blocks

First Posted Date
2015-06-03
Last Posted Date
2018-09-24
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
85
Registration Number
NCT02462148
Locations
🇺🇸

Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, United States

The Effect of the Serratus Block on Pain Control After Breast Surgery

First Posted Date
2015-05-25
Last Posted Date
2020-01-13
Lead Sponsor
Women's College Hospital
Target Recruit Count
40
Registration Number
NCT02453516
Locations
🇨🇦

Women's College Hospital, Toronto, Ontario, Canada

Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly

First Posted Date
2015-04-28
Last Posted Date
2018-04-13
Lead Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Target Recruit Count
1812
Registration Number
NCT02428062
Locations
🇮🇹

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico; Via F. Sforza 35, Milano, Italy

Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-04-21
Last Posted Date
2016-06-16
Lead Sponsor
Isabel Peixoto Tortamano
Target Recruit Count
90
Registration Number
NCT02422823
Locations
🇧🇷

Faculdade de Odontologia da USP, Sao Paulo, SP, Brazil

Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization

First Posted Date
2015-02-20
Last Posted Date
2016-08-19
Lead Sponsor
Helse Fonna
Target Recruit Count
34
Registration Number
NCT02368054
Locations
🇳🇴

Kirurgisk Klinikk-Anestesi, Haugesund, Rogaland, Norway

Hip Scope Fascia-iliaca (FI) Block Study

First Posted Date
2015-02-19
Last Posted Date
2019-03-14
Lead Sponsor
The Hawkins Foundation
Target Recruit Count
84
Registration Number
NCT02365961
Locations
🇺🇸

Steadman Hawkins Clinic of the Carolinas - Greenville Health System, Greenville, South Carolina, United States

Exparel vs Exparel Plus ACB in TKAs

First Posted Date
2015-02-19
Last Posted Date
2016-01-14
Lead Sponsor
The Hawkins Foundation
Registration Number
NCT02365727
Locations
🇺🇸

Steadman Hawkins Clinic of the Carolinas - Greenville Health System, Greenville, South Carolina, United States

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