Epinephrine
- Generic Name
- Epinephrine
- Brand Names
- Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13NO3
- CAS Number
- 51-43-4
- Unique Ingredient Identifier
- YKH834O4BH
- Background
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...
- Indication
Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
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- Associated Conditions
- Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
- Associated Therapies
- -
Addition of Clonidine to Ropivacaine in Adductor Canal Block
- Conditions
- Interventions
- First Posted Date
- 2017-02-17
- Last Posted Date
- 2018-05-03
- Lead Sponsor
- University of Vermont
- Target Recruit Count
- 80
- Registration Number
- NCT03057015
- Locations
- 🇺🇸
University of Vermont Medical Center, Burlington, Vermont, United States
Liposomal Bupivacaine for Pain Control Following Thoracic Surgery.
- First Posted Date
- 2017-01-30
- Last Posted Date
- 2017-01-30
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT03036085
Pharmacokinetics of Epinephrine During Cardiac Arrest
- First Posted Date
- 2017-01-30
- Last Posted Date
- 2019-08-21
- Lead Sponsor
- Haukeland University Hospital
- Target Recruit Count
- 8
- Registration Number
- NCT03036202
- Locations
- 🇳🇴
Haukeland University Hospital, Bergen, N, Norway
Conscious Sedation for Epilepsy Surgery
- Conditions
- Interventions
- First Posted Date
- 2016-12-09
- Last Posted Date
- 2020-10-09
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 60
- Registration Number
- NCT02988050
Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries
- Conditions
- Interventions
- First Posted Date
- 2016-12-02
- Last Posted Date
- 2022-09-22
- Lead Sponsor
- University at Buffalo
- Target Recruit Count
- 36
- Registration Number
- NCT02980835
- Locations
- 🇺🇸
VA Western New York Healthcare System, Buffalo, New York, United States
Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
- Conditions
- Interventions
- First Posted Date
- 2016-11-18
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- University of Iowa
- Target Recruit Count
- 100
- Registration Number
- NCT02967172
- Locations
- 🇺🇸
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Epinephrine Sprayed on the Papilla Versus Sterile Water Sprayed on the Papilla for Preventing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography
- Conditions
- Interventions
- First Posted Date
- 2016-11-08
- Last Posted Date
- 2020-02-12
- Target Recruit Count
- 548
- Registration Number
- NCT02959112
- Locations
- 🇲🇽
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Tlalpan, Mexico
Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size
- First Posted Date
- 2016-09-09
- Last Posted Date
- 2020-01-31
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 59
- Registration Number
- NCT02895035
The Effects of Low-dose Epinephrine Plus Tranexamic Acid on Perioperative Haemostasis and Inflammatory Reaction in Major Surgery
- First Posted Date
- 2016-08-11
- Last Posted Date
- 2017-07-31
- Lead Sponsor
- Southwest Hospital, China
- Target Recruit Count
- 200
- Registration Number
- NCT02864095
- Locations
- 🇨🇳
Southwest Hospital, Chongqing, Chongqing, China
Intravenous Versus Topical Administration of Low Dose Epinephrine Plus Combined Administration of Intravenous and Topical Tranexamic Acid (TXA)for Primary Total Knee Arthroplasty
- First Posted Date
- 2016-08-09
- Last Posted Date
- 2017-07-27
- Lead Sponsor
- Southwest Hospital, China
- Target Recruit Count
- 210
- Registration Number
- NCT02860221
- Locations
- 🇨🇳
Southwest Hospital, Chongqing, Chongqing, China
Drug Development Updates
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