Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-09-07
- Last Posted Date
- 2019-10-18
- Lead Sponsor
- Kootenai Health
- Target Recruit Count
- 239
- Registration Number
- NCT02543801
Influence of the Noradrenergic System on the Formation of Intrusive Memories
- Conditions
- Interventions
- First Posted Date
- 2015-09-04
- Last Posted Date
- 2015-09-04
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 118
- Registration Number
- NCT02541071
- Locations
- 🇩🇪
Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Efficacy, Safety and Pharmacokinetic Study of Intravenous Clonidine Versus Midazolam for Sedation in Paediatric Patients
- First Posted Date
- 2015-07-28
- Last Posted Date
- 2019-01-09
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Target Recruit Count
- 28
- Registration Number
- NCT02509273
- Locations
- 🇨🇿
Univerzita Karlova v Praze, Prague, Czechia
🇩🇪University of Erlangen-Nürnberg Medical School, Erlangen, Germany
🇪🇸Hospital Universitario 12 de Octubre, Madrid, Spain
Ropivacaine With Clonidine For Pediatric Rectus Sheath Blocks- The Magic Combination
- First Posted Date
- 2015-05-08
- Last Posted Date
- 2019-07-23
- Lead Sponsor
- Mihaela Visoiu
- Target Recruit Count
- 50
- Registration Number
- NCT02439281
- Locations
- 🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
Anesthetics in Rhytidoplasty - A Comparison Study
- First Posted Date
- 2015-04-07
- Last Posted Date
- 2015-04-07
- Lead Sponsor
- Mercy Facial Plastic Surgery Center
- Target Recruit Count
- 30
- Registration Number
- NCT02410460
- Locations
- 🇺🇸
Mercy Facial Plastic Surgery Center, Springfield, Missouri, United States
Use of Clonidine to Prevent Withdrawal Following Prolonged Dexmedetomidine Infusions
- First Posted Date
- 2015-03-31
- Last Posted Date
- 2017-04-20
- Lead Sponsor
- Joseph D. Tobias
- Target Recruit Count
- 712
- Registration Number
- NCT02404077
Hip Scope Fascia-iliaca (FI) Block Study
- Conditions
- Interventions
- First Posted Date
- 2015-02-19
- Last Posted Date
- 2019-03-14
- Lead Sponsor
- The Hawkins Foundation
- Target Recruit Count
- 84
- Registration Number
- NCT02365961
- Locations
- 🇺🇸
Steadman Hawkins Clinic of the Carolinas - Greenville Health System, Greenville, South Carolina, United States
Exparel vs Exparel Plus ACB in TKAs
- Conditions
- Interventions
- First Posted Date
- 2015-02-19
- Last Posted Date
- 2016-01-14
- Lead Sponsor
- The Hawkins Foundation
- Registration Number
- NCT02365727
- Locations
- 🇺🇸
Steadman Hawkins Clinic of the Carolinas - Greenville Health System, Greenville, South Carolina, United States
The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism
- Conditions
- Interventions
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2015-02-12
- Lead Sponsor
- Vilnius University
- Target Recruit Count
- 60
- Registration Number
- NCT02362256
- Locations
- 🇱🇹
Republic Vilnius University Hospital, Vilnius, Lithuania
Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?
- First Posted Date
- 2015-02-11
- Last Posted Date
- 2019-02-11
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 379
- Registration Number
- NCT02361476
- Locations
- 🇩🇰
Køge Sygehus, Anæstesiologisk Afdeling, Køge, Denmark
🇩🇰The Juliane Marie Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Zealand, Denmark
🇩🇰Anæstesiologisk afdeling, Vejle Sygehus, Vejle, Denmark
Drug Development Updates
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