Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Dexmedetpmidine Versus Ketamine for Postoperative Sore Throat in Sinus Surgery
- Conditions
- Interventions
- First Posted Date
- 2021-07-08
- Last Posted Date
- 2023-04-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 143
- Registration Number
- NCT04955158
- Locations
- 🇪🇬
Omar Soliman, Assuit, Egypt
Nitroglycerine Versus Dexmedetomidine Infusion in Intraoperative Management of Uncontrolled Hypertension
- First Posted Date
- 2021-07-07
- Last Posted Date
- 2023-01-10
- Lead Sponsor
- National Cancer Institute, Egypt
- Target Recruit Count
- 77
- Registration Number
- NCT04953156
- Locations
- 🇪🇬
National Cancer Institute, Cairo, Egypt
Intranasal Dexmedetomidine Versus Oral Paracetamol as a Pre-anaesthetic Medication in Pediatric Age Group
- First Posted Date
- 2021-07-02
- Last Posted Date
- 2022-05-06
- Lead Sponsor
- Benha University
- Target Recruit Count
- 86
- Registration Number
- NCT04949477
- Locations
- 🇪🇬
Banha Faculity of Medicine, Banhā, Elqalyoubea, Egypt
Mother's Recorded Voice Versus Dexmedetomidine on Postoperative Agitation
- Conditions
- Interventions
- First Posted Date
- 2021-06-28
- Last Posted Date
- 2021-11-18
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT04941508
- Locations
- 🇪🇬
Omar Soliman, Assuit, Egypt
🇪🇬Assiut university hospital, Assiut, Egypt
The Effect of Dexmedetomidine on Oxygen During One Lung Ventilation in Pediatric Surgery.
- Conditions
- Interventions
- First Posted Date
- 2021-06-21
- Last Posted Date
- 2023-02-17
- Lead Sponsor
- Damascus University
- Target Recruit Count
- 110
- Registration Number
- NCT04932746
- Locations
- 🇸🇾
University Children's Hospital, Damascus, Syrian Arab Republic
A Single Bolus of Dexmedetomidine Versus Nalbuphine in Postoperative Agitation
- Conditions
- Interventions
- First Posted Date
- 2021-06-16
- Last Posted Date
- 2024-05-17
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT04928391
- Locations
- 🇪🇬
Omar Soliman, Assiut, Assuit, Egypt
🇪🇬Assiut university hospital, Assiut, Egypt
Low Dose Dexmedetomidine Versus Ketamine in Multiple Fracture Ribs
- Conditions
- Interventions
- First Posted Date
- 2021-06-16
- Last Posted Date
- 2024-05-17
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT04928300
- Locations
- 🇪🇬
Assiut university hospital, Assiut, Assuit, Egypt
Efficacy of Adding Dexmedetomidine as an Adjuvant to Bupivacaine in TAP Block and Caudal Block
- First Posted Date
- 2021-06-15
- Last Posted Date
- 2021-10-14
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 50
- Registration Number
- NCT04926454
- Locations
- 🇪🇬
AinShams Hospitals, Cairo, Egypt
Immunomodulatory Effects of Dexmedetomidine Infusion
- Conditions
- Interventions
- First Posted Date
- 2021-06-11
- Last Posted Date
- 2022-06-01
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 100
- Registration Number
- NCT04923737
- Locations
- 🇪🇬
Rehab Abd Elraof Abd Elaziz, Alexandria, Egypt
A Randomized Single-blind Clinical Trial of the Efficacy and Safety of Remimazolam in Painless Bronchoscopy
- First Posted Date
- 2021-06-09
- Last Posted Date
- 2021-06-09
- Target Recruit Count
- 364
- Registration Number
- NCT04919174
- Locations
- 🇨🇳
The Second Affiliated Hospital of Zhejiang University Medical College, Hangzhou, Zhejiang, China
Drug Development Updates
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