Diclofenac
- Generic Name
- Diclofenac
- Brand Names
- Aleve Arthritis Pain, Arthrotec, Cambia, Cataflam, Flector, Licart, Lofena, Pennsaid, Previdolrx Analgesic Pak, Salonpas Pain Relieving Patch, Solaraze, Voltaren, Voltaren Emulgel, Xrylix, Zipsor, Zorvolex
- Drug Type
- Small Molecule
- Chemical Formula
- C14H11Cl2NO2
- CAS Number
- 15307-86-5
- Unique Ingredient Identifier
- 144O8QL0L1
- Background
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and in...
- Indication
Diclofenac is indicated for use in the treatment of pain and inflammation from varying sources including inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as injury-related inflammation due to surgery and physical trauma. It is often used in combination with misoprostol as a gastro-protective agent in p...
- Associated Conditions
- Actinic Keratosis (AK), Acute Arthritis, Acute Gouty Arthritis, Acute Migraine, Acute Musculoskeletal Pain, Ankylosing Spondylitis (AS), Common Cold, Fever, Gout, Inflammation, Inflammatory Disease of the Oral Cavity, Inflammatory Disease of the throat, Inflammatory Reaction of the Nerve, Joint Pain, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Muscle Inflammation, Myalgia, Neuropathic Pain, Ocular Inflammation, Osteoarthritis (OA), Osteoarthritis of the Knee, Pain, Pain caused by Rheumatism, Pericarditis, Photophobia, Postoperative Inflammatory Response, Postoperative pain, Primary Dysmenorrhoea, Radicular Pain, Rheumatism, Rheumatoid Arthritis, Seasonal Allergic Conjunctivitis, Spinal pain, Tendon pain, Vertebral column pain, Acute Musculoskeletal injury, Acute, moderate, severe Pain, Inflammatory, Localized soft tissue rheumatism, Mild to moderate joint pain, Mild to moderate pain, Minor pain, Perioperative miosis
- Associated Therapies
- -
To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal Morphine
- Conditions
- Interventions
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2017-05-09
- Lead Sponsor
- HaEmek Medical Center, Israel
- Target Recruit Count
- 200
- Registration Number
- NCT02440399
- Locations
- 🇮🇱
Haemek Medical Center, Afula, Israel
Tubal Flushing Using Water Soluble Media for Unexplained Infertility
- First Posted Date
- 2015-05-05
- Last Posted Date
- 2017-01-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 300
- Registration Number
- NCT02433418
- Locations
- 🇪🇬
BeniSuef University hospitals, BeniSuef, Egypt
🇪🇬Cairo University Hospitals, Cairo, Egypt
Tramadol Versus Diclofenac for Prevention of Pain in Operative Outpatient Hysteroscopy
- First Posted Date
- 2015-04-29
- Last Posted Date
- 2019-04-08
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 210
- Registration Number
- NCT02428777
- Locations
- 🇪🇬
BeniSuef University hospitals, BeniSuef, Egypt
🇪🇬Cairo university hospitals, Cairo, Egypt
Tramadol Versus Diclofenac for Reducing Pain Before Outpatient Hysteroscopy in Post Menopausal Women
- First Posted Date
- 2015-04-24
- Last Posted Date
- 2017-01-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 210
- Registration Number
- NCT02425709
- Locations
- 🇪🇬
Cairo university hospitals, Cairo, Egypt
Tramadol Versus Diclofenac for Reducing Pain Before Outpatient Hysteroscopy
- Conditions
- Interventions
- First Posted Date
- 2015-04-17
- Last Posted Date
- 2017-01-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 210
- Registration Number
- NCT02419651
- Locations
- 🇪🇬
Cairo University Hospitals, Cairo, Egypt
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
- Conditions
- Interventions
- First Posted Date
- 2015-04-15
- Last Posted Date
- 2015-04-15
- Lead Sponsor
- University of Khartoum
- Target Recruit Count
- 170
- Registration Number
- NCT02417337
- Locations
- 🇸🇩
University of Khartoum, Faculty of Dentistry,, Khartoum, Sudan
The Real Life Topical Field Treatment of Actinic Keratosis Study
- Conditions
- Interventions
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2019-12-13
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 1168
- Registration Number
- NCT02362152
- Locations
- 🇳🇱
Lievensberg Ziekenhuis, Bergen op Zoom, Netherlands
Dabigatran in an Interaction Probe Drug Cocktail
- Conditions
- Interventions
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2018-08-14
- Lead Sponsor
- Turku University Hospital
- Target Recruit Count
- 16
- Registration Number
- NCT02361619
- Locations
- 🇫🇮
Teutori CPRU, Turku, Finland
Clinical Efficacy and Safety of Benjakul Recipe in Treating Primary Osteoarthritis of Knee Compared With Diclofenac
- First Posted Date
- 2014-11-07
- Last Posted Date
- 2015-09-29
- Lead Sponsor
- Thammasat University
- Target Recruit Count
- 84
- Registration Number
- NCT02286453
- Locations
- 🇹🇭
Thammasat University (Ruangsit campus), Khlong Luang, Pathum Thani, Thailand
Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrhea
- Conditions
- Interventions
- First Posted Date
- 2014-10-02
- Last Posted Date
- 2019-05-03
- Lead Sponsor
- Laboratorios Andromaco S.A.
- Target Recruit Count
- 68
- Registration Number
- NCT02255045
- Locations
- 🇨🇱
Instituto Chileno de Medicina Reproductiva (ICMER), Santiago, Chile
Drug Development Updates
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