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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
Radiation: Standard radiotherapy
First Posted Date
2008-11-24
Last Posted Date
2016-08-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
62
Registration Number
NCT00796718

CLEAR Study - A Study of CellCept (Mycophenolate Mofetil) in Recipients of Kidney Transplants

Phase 3
Completed
Conditions
Kidney Transplantation
Interventions
First Posted Date
2008-11-11
Last Posted Date
2015-11-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
136
Registration Number
NCT00788567

Safety, Tolerability, and Antiviral Activity of ANA598 in Patients With Genotype-1 Chronic HCV Infection

Phase 1
Completed
Conditions
Chronic Hepatitis C
Interventions
Drug: ANA598 200 mg bid or placebo
Drug: ANA598 400 mg bid or placebo
Drug: ANA598 800 mg bid or placebo
First Posted Date
2008-10-31
Last Posted Date
2012-11-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
35
Registration Number
NCT00782353
Locations
🇺🇸

United States, Missouri, St. Louis, Missouri, United States

🇺🇸

United States, New York, New York, New York, United States

🇵🇷

Puerto Rico, Santurce, Santurce, Puerto Rico

and more 1 locations

A Study of Avastin (Bevacizumab) in Combination With mFOLFOX-6 or FOLFOXIRI in Patients With Metastatic Colorectal Cancer.

First Posted Date
2008-10-23
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT00778102

A Study of Avastin (Bevacizumab) in Combination With Thoracic Radiation and Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.

Phase 1
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2008-10-21
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1
Registration Number
NCT00776698

A Study of the Quality of Life and Treatment Response to Once Weekly Epoetin Beta (Recormon) Treatment in Anemic Participants With Solid and Lymphoid Malignancies

Phase 4
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-10-21
Last Posted Date
2017-07-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
117
Registration Number
NCT00776425

PRIMADOS Study:A Study of Avastin (Bevacizumab) Plus Docetaxel for First Line Treatment of Patients With Metastatic Breast Cancer

Phase 4
Withdrawn
Conditions
Breast Cancer
Interventions
First Posted Date
2008-10-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00774241

A Study of Bevacizumab (Avastin) in Combination With Neoadjuvant Treatment Regimens in Participants With Primary Human Epidermal Growth Factor Receptor 2 (HER2) Negative Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2008-10-16
Last Posted Date
2023-01-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
150
Registration Number
NCT00773695
Locations
🇳🇴

Ullevael Sykehus; Dept of Oncology, Oslo, Norway

🇳🇴

The Norvegian Radium Hospital Montebello; Dept of Oncology, Oslo, Norway

🇳🇴

St. Olavs Hospital; Kreftavdelingen, Trondheim, Norway

A Study of Monthly Subcutaneous Continuous Erythropoietin Receptor Activator (CERA) in Predialysis Participants With Chronic Renal Anemia

Phase 3
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-10-16
Last Posted Date
2016-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
140
Registration Number
NCT00773968

A Dose-Escalation Study of RO5126766 in Patients With Advanced Solid Tumors.

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2008-10-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT00773526
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