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M.D. ANDERSON CANCER CENTER

🇺🇸United States
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Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2018-07-13
Last Posted Date
2025-04-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
145
Registration Number
NCT03586609
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Locally Advanced, Metastatic, or Recurrent Cancer

Phase 2
Active, not recruiting
Conditions
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid System Neoplasm
Locally Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Recurrent Malignant Solid Neoplasm
Interventions
Behavioral: Exercise Intervention
Other: Placebo Administration
First Posted Date
2018-07-11
Last Posted Date
2025-06-05
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
99
Registration Number
NCT03583255
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

Phase 3
Recruiting
Conditions
ENSAT Stage I Adrenal Cortex Carcinoma
ENSAT Stage II Adrenal Cortex Carcinoma
ENSAT Stage III Adrenal Cortex Carcinoma
Interventions
Other: Quality-of-Life Assessment
First Posted Date
2018-07-11
Last Posted Date
2025-06-04
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
240
Registration Number
NCT03583710
Locations
🇸🇪

Sahlgrenska University Hospital, Gothenburg, Sweden

🇸🇪

Karolinska University Hospital, Stockholm, Sweden

🇸🇪

Akademiska Sjukhuset, Uppsala, Sweden

and more 5 locations

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Predicting Treatment Response in Patients With Prostate Cancer

Phase 2
Withdrawn
Conditions
PSA Level Greater Than Ten
Stage IIIB Prostate Cancer AJCC v8
Stage IIIC Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Prostate Adenocarcinoma
Stage III Prostate Cancer AJCC v8
Stage IIB Prostate Cancer AJCC v8
Stage IIIA Prostate Cancer AJCC v8
Interventions
Procedure: Magnetic Resonance Spectroscopic Imaging
First Posted Date
2018-07-10
Last Posted Date
2025-04-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
2
Registration Number
NCT03581500
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Phase 1
Active, not recruiting
Conditions
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Interventions
First Posted Date
2018-07-10
Last Posted Date
2025-05-31
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT03581487
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

CD19-Specific T Cells Post AlloSCT

Phase 1
Terminated
Conditions
B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged
Recurrent B Acute Lymphoblastic Leukemia
Recurrent Ph-Like Acute Lymphoblastic Leukemia
Refractory Small Lymphocytic Lymphoma
Recurrent Non-Hodgkin Lymphoma
Refractory B Acute Lymphoblastic Leukemia
Recurrent Small Lymphocytic Lymphoma
Refractory Chronic Lymphocytic Leukemia
Recurrent Chronic Lymphocytic Leukemia
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Interventions
Biological: Autologous CD19-CD8-CD28-CD3zeta-CAR-mbIL15-HER1t T Cells
First Posted Date
2018-07-09
Last Posted Date
2021-06-02
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
4
Registration Number
NCT03579888
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma

Phase 1
Withdrawn
Conditions
Recurrent Diffuse Large B-Cell Lymphoma
Refractory Follicular Lymphoma
CD19 Positive
Refractory Diffuse Large B-Cell Lymphoma
Mantle Cell Lymphoma
Refractory B-Cell Non-Hodgkin Lymphoma
Recurrent Follicular Lymphoma
Interventions
Procedure: Autologous Hematopoietic Stem Cell Transplantation
Biological: Filgrastim
Biological: Rituximab
Biological: Umbilical Cord Blood-derived Natural Killer Cells
First Posted Date
2018-07-09
Last Posted Date
2020-01-29
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT03579927
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

Early Phase 1
Active, not recruiting
Conditions
Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Interventions
First Posted Date
2018-07-06
Last Posted Date
2025-03-25
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
43
Registration Number
NCT03579446
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2
Active, not recruiting
Conditions
Recurrent Primary Peritoneal Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Fallopian Tube Carcinoma
Interventions
First Posted Date
2018-07-06
Last Posted Date
2025-02-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
96
Registration Number
NCT03579316
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

M7824 and Eribulin Mesylate in Treating Patients With Metastatic Triple Negative Breast Cancer

Phase 1
Terminated
Conditions
Prognostic Stage IV Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Triple-Negative Breast Carcinoma
Interventions
First Posted Date
2018-07-06
Last Posted Date
2022-10-31
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
38
Registration Number
NCT03579472
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

🇺🇸

Lyndon Baines Johnson General Hospital, Houston, Texas, United States

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