Nifedipine

Generic Name
Nifedipine
Brand Names
Adalat, Afeditab CR, Nifediac, Nifedical, Procardia
Drug Type
Small Molecule
Chemical Formula
C17H18N2O6
CAS Number
21829-25-4
Unique Ingredient Identifier
I9ZF7L6G2L
Background

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and lo...

Indication

Nifedipine capsules are indicated to treat vasospastic angina and chronic stable angina. Extended release tablets are indicated to treat vasospastic angina, chronic stable angina, and hypertension.

Associated Conditions
Achalasia, Chronic Stable Angina Pectoris, Fissure;Anal, Hypertension, Hypertensive Emergency, Premature Labour, Proctalgia, Pulmonary Edemas, Pulmonary Hypertension (PH), Raynaud's Phenomenon, Ureteral Calculus, Vasospastic Angina
Associated Therapies
-

Genetic Polymorphisms of ABCG2/BCRP on the Transport of Nifedipine to Breast Milk.

First Posted Date
2018-10-18
Last Posted Date
2018-10-18
Lead Sponsor
Natalia Valadares de Moraes
Target Recruit Count
19
Registration Number
NCT03710395

Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa

Phase 3
Completed
Conditions
Interventions
First Posted Date
2018-05-31
Last Posted Date
2021-07-28
Lead Sponsor
Assiut University
Target Recruit Count
176
Registration Number
NCT03542552
Locations
🇪🇬

Assiut university, Assiut, Egypt

Response to Anti-hypertensives in Pregnant and Postpartum Patients

First Posted Date
2018-04-24
Last Posted Date
2021-05-24
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
109
Registration Number
NCT03506724
Locations
🇺🇸

Maimonides Hospital, Brooklyn, New York, United States

🇺🇸

Mount Sinai West, New York, New York, United States

Comparison of Nifedipine Versus Indomethacin for Acute Preterm Labor

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2017-04-26
Last Posted Date
2021-11-05
Lead Sponsor
University of California, Irvine
Target Recruit Count
36
Registration Number
NCT03129945
Locations
🇺🇸

University of California, Davis, Sacramento, California, United States

🇺🇸

University of California, Irvine, Orange, California, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

and more 2 locations

The Effect of Zinc, β-carotene, and Vitamin D3 in Preterm Delivery Through Placental MyD88, TRIF, NFkB, and IL-1β

First Posted Date
2016-12-29
Last Posted Date
2017-11-21
Lead Sponsor
Indonesia University
Target Recruit Count
56
Registration Number
NCT03005496

Changes in Central Arterial Pressure When Comparing ACOG Hypertensive Urgency Protocols

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2016-10-14
Last Posted Date
2017-11-13
Lead Sponsor
St. Louis University
Registration Number
NCT02933593

Role of Calcium Channels in Vascular Function

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2016-08-31
Last Posted Date
2021-06-01
Lead Sponsor
University of Southern Denmark
Target Recruit Count
12
Registration Number
NCT02885558
Locations
🇩🇰

Centre for Phsical Activity Research, Copenhagen, Denmark

🇩🇰

Cardiovascular and Renal Research, Odense, Denmark

Tocolytic Therapy for Preterm Labor in Multiple Gestation

First Posted Date
2016-04-01
Last Posted Date
2016-04-01
Lead Sponsor
Tel-Aviv Sourasky Medical Center
Target Recruit Count
140
Registration Number
NCT02725736

Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow

First Posted Date
2015-10-29
Last Posted Date
2017-11-17
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
130
Registration Number
NCT02591004
Locations
🇪🇬

11562, Cairo, Egypt

© Copyright 2024. All Rights Reserved by MedPath