Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy

Phase 4

Completed

Conditions: Supratentorial Neoplasms

Interventions: Drug: Remifentanil
Drug: Propofol

First Posted Date: 2015-11-01

Last Posted Date: 2015-11-01

Lead Sponsor: Yeditepe University Hospital

Target Recruit Count: 80

Registration Number: NCT02593942

Locations: 🇹🇷
Yeditepe University Hospital, Istanbul, Turkey

Gender and PK-PD of Propofol and Cisatracurium

Completed

Conditions: Gender

Interventions: Drug: propofol
Drug: Cisatracurium

First Posted Date: 2015-10-27

Last Posted Date: 2019-08-12

Lead Sponsor: Medical University of Graz

Target Recruit Count: 120

Registration Number: NCT02588118

Locations: 🇨🇳
Xijing hospital of Fourth Military Medical University, Xi'an, Shaanxi, China
🇦🇹
Medical University of Graz, Graz, Austria

Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General Anesthesia

Phase 4

Conditions: Anesthesia

Interventions: Device: Electroencephalography
Drug: Propofol
Drug: Rocuronium bromide

First Posted Date: 2015-10-26

Last Posted Date: 2015-11-04

Lead Sponsor: Korea University Anam Hospital

Target Recruit Count: 40

Registration Number: NCT02586441

Effect of Ketamine+Propofol vs Remifentanyl+Propofol on Laryngeal Mask Insertion Conditions

Completed

Conditions: Surgery

Interventions: Drug: Ketamine
Drug: remifentanyl
Drug: propofol
Device: laryngeal mask

First Posted Date: 2015-10-22

Last Posted Date: 2017-05-08

Lead Sponsor: Ankara University

Target Recruit Count: 50

Registration Number: NCT02583217

Locations: 🇹🇷
Cigdem Yildirim Guclu, Ankara, Turkey

Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction

Not Applicable

Completed

Conditions: Rupture of Anterior Cruciate Ligament
Tear of Anterior Cruciate Ligament

Interventions: Drug: Mepivacaine
Procedure: adductor canal continuous nerve catheter
Procedure: adductor canal nerve block
Drug: Normal Saline as bolus followed by bupivacaine
Drug: ropivacaine and dexamethasone
Drug: Propofol
Drug: Fentanyl