Verapamil

Generic Name
Verapamil
Brand Names
Calan, Isoptin, Tarka, Verelan
Drug Type
Small Molecule
Chemical Formula
C27H38N2O4
CAS Number
52-53-9
Unique Ingredient Identifier
CJ0O37KU29
Background

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like diltiazem and flunarizine, bu...

Indication

Verapamil is indicated in the treatment of vasopastic (i.e. Prinzmetal's) angina, unstable angina, and chronic stable angina. It is also indicated to treat hypertension, for the prophylaxis of repetitive paroxysmal supraventricular tachycardia, and in combination with digoxin to control ventricular rate in patients with atrial fibrillation or atrial flutter....

Associated Conditions
Chronic Stable Angina Pectoris, Cluster Headache, Heart Rate, Hypertension, Paroxysmal Supraventricular Tachycardia (PSVT), Supra-ventricular Tachyarrhythmias, Unstable Angina Pectoris, Vasospastic Angina
Associated Therapies
-
Clinical Trials
Related News

CiPA Phase 1 ECG Biomarker Validation Study

First Posted Date
2017-03-03
Last Posted Date
2020-01-18
Lead Sponsor
Food and Drug Administration (FDA)
Target Recruit Count
60
Registration Number
NCT03070470
Locations
🇺🇸

Spaulding Clinical Research, West Bend, Wisconsin, United States

Intracavernosal Injection of Papaverine/Verapamil Versus Papaverine/Phentolamine in Erectile Dysfunction

Completed
Conditions
Erectile Dysfunction
Interventions
Drug: Verapamil
First Posted Date
2017-01-27
Last Posted Date
2017-01-27
Lead Sponsor
Adam International Hospital
Target Recruit Count
20
Registration Number
NCT03033537

Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

First Posted Date
2017-01-09
Last Posted Date
2024-02-22
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
29
Registration Number
NCT03013933
Locations
🇺🇸

City of Hope Medical Center, Duarte, California, United States

Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population

First Posted Date
2016-05-13
Last Posted Date
2016-09-09
Lead Sponsor
Meshalkin Research Institute of Pathology of Circulation
Target Recruit Count
124
Registration Number
NCT02772354
Locations
🇷🇺

State Research Institute of CIrculation Pathology Novosibirsk, Russian Federation, Novosibirsk, Russian Federation

🇷🇺

Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation

A Phase I Study to Assess PK of AZD7986 Alone & With Verapamil, Itraconazole or Diltiazem in Healthy Subjects

First Posted Date
2016-01-12
Last Posted Date
2018-02-23
Lead Sponsor
AstraZeneca
Target Recruit Count
15
Registration Number
NCT02653872
Locations
🇬🇧

Research Site, London, United Kingdom

Verapamil vs Heparin in Transradial Procedures

Phase 4
Completed
Conditions
Heart Disease, Ischemic
Interventions
Drug: Verapamil
Drug: Heparin
First Posted Date
2015-05-27
Last Posted Date
2016-10-04
Lead Sponsor
University Hospital of Ferrara
Target Recruit Count
418
Registration Number
NCT02454491
Locations
🇮🇹

University Hospital of Ferrara, Cona, Ferrara, Italy

Verapamil for Beta Cell Survival Therapy in Type 1 Diabetes

Phase 2
Completed
Conditions
Type 1 Diabetes Mellitus
Interventions
Drug: Placebo
Drug: Verapamil
First Posted Date
2015-02-26
Last Posted Date
2020-02-05
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
32
Registration Number
NCT02372253
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

First Posted Date
2014-09-25
Last Posted Date
2020-01-21
Lead Sponsor
Maastricht University Medical Center
Target Recruit Count
437
Registration Number
NCT02248753
Locations
🇳🇱

VU University Medical Center, Amsterdam, Netherlands

🇳🇱

Antonius Ziekenhuis, Sneek, Netherlands

🇳🇱

University Medical Center Groningen, Groningen, Netherlands

and more 12 locations

Superselective Administration of VErapamil During Recanalization in Acute Ischemic Stroke

Phase 1
Completed
Conditions
Ischemic Stroke
Interventions
Drug: Verapamil
First Posted Date
2014-09-10
Last Posted Date
2017-01-23
Lead Sponsor
Justin Fraser
Target Recruit Count
11
Registration Number
NCT02235558
Locations
🇺🇸

University of Kentucky Deparment of Neurosurgery, UK Chandler Hospital, Lexington, Kentucky, United States

Relative Bioavailability of Single Oral Doses of Dabigatran Etexilate With or Without Oral Administration of Verapamil in Two Different Dosages in Healthy Male and Female Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: dabigatran
Drug: Verapamil
Drug: Verapamil ER
First Posted Date
2014-06-24
Last Posted Date
2014-06-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
40
Registration Number
NCT02171533
© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy