Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
Early Treatment Versus Expectant Management of PDA in Preterm Infants
- Conditions
- Interventions
- First Posted Date
- 2019-03-04
- Last Posted Date
- 2022-04-13
- Lead Sponsor
- Lviv National Medical University
- Target Recruit Count
- 208
- Registration Number
- NCT03860428
- Locations
- 🇺🇦
Lviv National Medical University, Lviv, Ukraine
A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.
- Conditions
- Interventions
- First Posted Date
- 2019-03-04
- Last Posted Date
- 2022-05-31
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 198
- Registration Number
- NCT03861611
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Pre-emptive Analgesic Administration in Primary Tooth Extraction
- Conditions
- Interventions
- First Posted Date
- 2018-12-24
- Last Posted Date
- 2019-06-18
- Lead Sponsor
- Tishreen University
- Target Recruit Count
- 66
- Registration Number
- NCT03786029
- Locations
- 🇸🇾
Tishreen University, Latakia, Syrian Arab Republic
Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy
- Conditions
- Interventions
- First Posted Date
- 2018-12-21
- Last Posted Date
- 2019-04-03
- Lead Sponsor
- Inonu University
- Target Recruit Count
- 60
- Registration Number
- NCT03783312
- Locations
- 🇹🇷
Erol Karaaslan, Malatya, Türkiye-Türkçe, Turkey
Ibuprofen IV vs Acetaminophen IV for the Treatment of Pain Following Orthopaedic Low Extremity Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-12-11
- Last Posted Date
- 2020-08-20
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 62
- Registration Number
- NCT03771755
- Locations
- 🇮🇩
Cipto Mangunkusumo Cental National Hospital, Jakarta, DKI Jakarta, Indonesia
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
- Conditions
- Interventions
- First Posted Date
- 2018-12-07
- Last Posted Date
- 2023-04-10
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 710
- Registration Number
- NCT03767933
- Locations
- 🇨🇦
Children's Hospital of Winnipeg, Winnipeg, Manitoba, Canada
🇨🇦Stollery Children's Hospital Emergency Department, Edmonton, Alberta, Canada
🇨🇦Alberta Children's Hospital, Calgary, Alberta, Canada
Supracondylar Post-Operative Pain Study
- Conditions
- Interventions
- First Posted Date
- 2018-11-29
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- University of California, Los Angeles
- Target Recruit Count
- 90
- Registration Number
- NCT03759028
- Locations
- 🇺🇸
Orthopaedic Institute for Children, Los Angeles, California, United States
Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture
- First Posted Date
- 2018-11-21
- Last Posted Date
- 2023-10-04
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 32
- Registration Number
- NCT03749616
- Locations
- 🇺🇸
University of Missouri Health Care, Columbia, Missouri, United States
Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea
- Conditions
- Interventions
- First Posted Date
- 2018-10-05
- Last Posted Date
- 2018-10-05
- Lead Sponsor
- Pamukkale University
- Target Recruit Count
- 300
- Registration Number
- NCT03697746
- Locations
- 🇹🇷
Pamukkale University, Deni̇zli̇, Turkey
Phase 2 Herniorrhaphy Study for Opioid Elimination
- Conditions
- Interventions
- First Posted Date
- 2018-10-04
- Last Posted Date
- 2021-10-25
- Lead Sponsor
- Heron Therapeutics
- Target Recruit Count
- 63
- Registration Number
- NCT03695367
- Locations
- 🇺🇸
Anaheim Clinical Trials, LLC, Anaheim, California, United States
🇺🇸Lotus Clinical Research, LLC, Pasadena, California, United States
🇺🇸JBR Clinical Research, Salt Lake City, Utah, United States
Drug Development Updates
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