Ibuprofen

Generic Name
Ibuprofen
Brand Names
Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
Drug Type
Small Molecule
Chemical Formula
C13H18O2
CAS Number
15687-27-1
Unique Ingredient Identifier
WK2XYI10QM
Background

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication

Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions
Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
Associated Therapies
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Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery

First Posted Date
2019-05-22
Last Posted Date
2021-04-01
Lead Sponsor
Medstar Health Research Institute
Target Recruit Count
48
Registration Number
NCT03959969
Locations
🇺🇸

Washington Hospital Center, Washington, District of Columbia, United States

HTX-011 Administration Study in Planned Caesarean Section Procedure

First Posted Date
2019-05-20
Last Posted Date
2022-03-14
Lead Sponsor
Heron Therapeutics
Target Recruit Count
25
Registration Number
NCT03955211
Locations
🇺🇸

Sharp Mary Birch Hospital for Women and Newborns, San Diego, California, United States

🇺🇸

UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States

🇺🇸

Helen Keller Hospital, Sheffield, Alabama, United States

and more 1 locations

Effectiveness of Pre-emptive Analgesia in Children With Molar-incisor Hypomineralization (MIH)

Early Phase 1
Conditions
Interventions
First Posted Date
2019-05-17
Last Posted Date
2021-09-28
Lead Sponsor
University of Sao Paulo
Target Recruit Count
50
Registration Number
NCT03953729
Locations
🇧🇷

School of Dentistry of Ribeirao Preto, Ribeirão Preto, São Paulo, Brazil

Treating Postictal Symptoms Using Ibuprofen and Nifedipine

First Posted Date
2019-05-14
Last Posted Date
2024-05-09
Lead Sponsor
University of Calgary
Target Recruit Count
90
Registration Number
NCT03949478
Locations
🇨🇦

Foothills Medical Centre, Calgary, Alberta, Canada

🇨🇦

South Health Campus, Calgary, Alberta, Canada

Management Of Pain After Cesarean Trial

First Posted Date
2019-04-29
Last Posted Date
2023-10-05
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
49
Registration Number
NCT03929640
Locations
🇺🇸

Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States

Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection

Phase 4
Completed
Conditions
Interventions
First Posted Date
2019-04-17
Last Posted Date
2021-03-09
Lead Sponsor
Pamukkale University
Target Recruit Count
200
Registration Number
NCT03918135
Locations
🇹🇷

Pamukkale University, Denizli, Turkey

Herniorrhaphy Study for Opioid Elimination

First Posted Date
2019-04-08
Last Posted Date
2022-02-21
Lead Sponsor
Heron Therapeutics
Target Recruit Count
115
Registration Number
NCT03907176
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

🇺🇸

UPMC Shadyside Hospital, Pittsburgh, Pennsylvania, United States

🇺🇸

UPMC Passavant, Pittsburgh, Pennsylvania, United States

and more 26 locations

Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction

First Posted Date
2019-03-28
Last Posted Date
2022-04-19
Lead Sponsor
University of Pennsylvania
Target Recruit Count
86
Registration Number
NCT03893175
Locations
🇺🇸

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States

Multi-dose Ibuprofen Prophylaxis for IUD-insertion

Not Applicable
Conditions
Interventions
First Posted Date
2019-03-08
Last Posted Date
2020-10-09
Lead Sponsor
Orlando VA Medical Center
Target Recruit Count
86
Registration Number
NCT03868137
Locations
🇺🇸

Orlando VA Medical Center, Orlando, Florida, United States

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