Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
2nd Department of Anesthesiology, Attikon University Hospital, Athens, Attiki, Greece
Department of Plastic Surgery, Mayo Hospital, King Edward Medical University, Lahore, Punjab, Pakistan
Recep Tayyip Erdogan University, Rize, Eastern Blacksea, Turkey
IRCCS Burlo Garofolo, Trieste, Friuli Venezia Giulia, Italy
UNIVERSITY OF DEBRECEN FACULTY OF MEDICINE Department of Anesthesiology and Intensive Care, Debrecen, Hajdú-Bihar, Hungary
Haemek Medical Center, Afula, Israel
BeniSuef University hospitals, BeniSuef, Egypt
Cairo university hospitals, Cairo, Egypt
Cairo university hospitals, Cairo, Egypt
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