Tramadol

Generic Name
Tramadol
Brand Names
Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
Drug Type
Small Molecule
Chemical Formula
C16H25NO2
CAS Number
27203-92-5
Unique Ingredient Identifier
39J1LGJ30J
Background

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...

Indication

Tramadol is approved for the management of moderate to severe pain in adults.

Tramadol is also used off-label in the treatment of premature ejaculation.

Associated Conditions
Acute Pain, Premature Ejaculation, Severe Pain, Acute, moderate, severe Pain, Moderate Pain
Associated Therapies
-

Tramadol in Penial Block Does it Improve Efficiency of Postoperative Analgesia in Circumcision

First Posted Date
2017-08-24
Last Posted Date
2017-08-24
Lead Sponsor
Leila mansali stambouli
Target Recruit Count
106
Registration Number
NCT03260439
Locations
🇹🇳

University Hospital of Fattouma Bourguiba, Monastir, Monastir- Tunisia, Tunisia

The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma

First Posted Date
2017-08-21
Last Posted Date
2019-03-07
Lead Sponsor
Masaryk University
Registration Number
NCT03255330
Locations
🇨🇿

Fakultní nemocnice Brno, Brno, Czechia

Postoperative Effects of TAP Block Versus QLB Type 2 Block

First Posted Date
2017-04-24
Last Posted Date
2017-11-14
Lead Sponsor
Bozyaka Training and Research Hospital
Target Recruit Count
90
Registration Number
NCT03126084
Locations
🇹🇷

Izmir Bozyaka Training and Research Hospital, Izmir, Turkey

Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain

First Posted Date
2017-03-01
Last Posted Date
2017-05-03
Lead Sponsor
Universidade Federal de Goias
Target Recruit Count
108
Registration Number
NCT03067103
Locations
🇧🇷

Juliana Alves de Sousa Caixeta, Anápolis, GO, Brazil

Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial

First Posted Date
2016-12-21
Last Posted Date
2016-12-23
Lead Sponsor
Maulana Azad Medical College
Target Recruit Count
86
Registration Number
NCT02999594

Efficacy and Safety in a Randomised Acute Pain Study of MR308 (Tramadol/Celecoxib).

Phase 3
Completed
Conditions
Interventions
First Posted Date
2016-12-05
Last Posted Date
2018-05-29
Lead Sponsor
Mundipharma Research GmbH & Co KG
Target Recruit Count
818
Registration Number
NCT02982161
Locations
🇵🇱

POLIMEDICA Centrum Badań, Profilaktyki i Leczenia Sp. z o.o. Sp. k., Zgierz, Poland

🇨🇦

Medical Arts Health Research Group, Penticton, Canada

🇩🇪

University Hospital Greifswald, Greifswald, Germany

and more 4 locations

SPI-directed Analgesia for Lumbar Discectomy

First Posted Date
2016-11-23
Last Posted Date
2019-04-16
Lead Sponsor
Medical University of Silesia
Target Recruit Count
132
Registration Number
NCT02971540
Locations
🇵🇱

Medical University of Silesia, Sosnowiec, Silesia, Poland

Advantage of Tramadol in Local Analgesia Post-Sternotomy

First Posted Date
2016-08-01
Last Posted Date
2017-10-10
Lead Sponsor
Centre Hospitalier Universitaire Dijon
Target Recruit Count
160
Registration Number
NCT02851394
Locations
🇫🇷

CHU Dijon Bourgogne, Dijon, France

A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair

First Posted Date
2016-07-29
Last Posted Date
2016-07-29
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
180
Registration Number
NCT02850211
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