Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
Virginia Commonwealth University, Richmond, Virginia, United States
Memorial Hermann Kirby Glen Surgery Center, Houston, Texas, United States
Wolfson medical center, Holon, Israel
Rush University Medical Center, Chicago, Illinois, United States
Aljazeerah Hospital, Giza, Egypt
Dept.of Anesthesia and Intensive Care, Warsaw Medical University, Warsaw, Mazowieckie, Poland
The University of Texas Health Science Center at Houston, Houston, Texas, United States
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