Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies
- Conditions
- First Posted Date
- 2016-09-08
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- University of New Mexico
- Target Recruit Count
- 1037352
- Registration Number
- NCT02893371
- Locations
- 🇺🇸
Christophe G Lambert, Albuquerque, New Mexico, United States
Sertraline and Cytosine Arabinoside in Adults With Relapsed and Refractory AML
- Conditions
- Interventions
- First Posted Date
- 2016-09-07
- Last Posted Date
- 2023-04-12
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 6
- Registration Number
- NCT02891278
- Locations
- 🇺🇸
Johns Hopkins University Medical Center, Baltimore, Maryland, United States
🇺🇸Columbia University, New York, New York, United States
Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)
- Conditions
- Interventions
- First Posted Date
- 2016-06-27
- Last Posted Date
- 2021-09-10
- Lead Sponsor
- Duke University
- Target Recruit Count
- 15
- Registration Number
- NCT02813447
- Locations
- 🇺🇸
Duke Pulmonary Rehabilitation, Durham, North Carolina, United States
Effects of Sertraline on Brain Connectivity in Adolescents With OCD
- First Posted Date
- 2016-06-13
- Last Posted Date
- 2021-01-05
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 41
- Registration Number
- NCT02797808
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Stress & Premenstrual Symptoms Study
- First Posted Date
- 2016-05-19
- Last Posted Date
- 2022-11-17
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 84
- Registration Number
- NCT02777372
- Locations
- 🇺🇸
Center for Women's Reproductive Mental Health, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma
- First Posted Date
- 2016-05-12
- Last Posted Date
- 2021-10-05
- Lead Sponsor
- University of Ulm
- Target Recruit Count
- 10
- Registration Number
- NCT02770378
- Locations
- 🇩🇪
University of Ulm School of Medicine, Ulm, Baden-Württemberg, Germany
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
- Conditions
- Interventions
- First Posted Date
- 2016-01-14
- Last Posted Date
- 2021-07-02
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 635
- Registration Number
- NCT02655354
- Locations
- 🇺🇸
Jacobi Medical Center, Bronx, New York, United States
🇺🇸University of Rochester, Rochester, New York, United States
🇺🇸Honor Health, Scottsdale, Arizona, United States
Study to Evaluate The Effect Of Sertraline on the Cardiac Repolarization in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2016-01-11
- Last Posted Date
- 2021-01-27
- Target Recruit Count
- 54
- Registration Number
- NCT02651623
- Locations
- 🇧🇪
Pfizer Clinical Research Unit, Brussels, Belgium
A Randomized Controlled Trial of Sertraline in Paroxysmal Arterial Hypertension
- First Posted Date
- 2015-12-29
- Last Posted Date
- 2017-09-08
- Lead Sponsor
- University Hospital Olomouc
- Target Recruit Count
- 136
- Registration Number
- NCT02641652
Efficacy of Nepeta Menthoides Extract on Anxiety of Patients With Depression: a Double-blind Randomized Controlled Clinical Trial
- Conditions
- Interventions
- First Posted Date
- 2015-10-01
- Last Posted Date
- 2015-10-01
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 70
- Registration Number
- NCT02565316
Drug Development Updates
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