Hydrocodone

Generic Name
Hydrocodone
Brand Names
Dalmacol, Hycet, Hycodan, Hydromet, Hysingla, Lorcet, Lortab, Norco, Obredon, Reprexain, Tussicaps, Tussionex, Vicoprofen, Xodol, Zamicet, Zohydro, Zydone
Drug Type
Small Molecule
Chemical Formula
C18H21NO3
CAS Number
125-29-1
Unique Ingredient Identifier
6YKS4Y3WQ7
Background

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphon...

Indication

Hydrocodone is indicated for the management of acute pain, sometimes in combination with acetaminophen or ibuprofen, as well as the symptomatic treatment of the common cold and allergic rhinitis in combination with decongestants, antihistamines, and expectorants.

Associated Conditions
Acute Pain, Chronic Pain, Cough, Cough caused by Allergic Rhinitis, Cough caused by Common Cold, Nasal Congestion caused by Allergic Rhinitis, Nasal Congestion caused by Common Cold, Rhinitis caused by Common Cold, Severe Pain, Moderate Pain, Upper respiratory symptoms caused by Allergic Rhinitis, Upper respiratory symptoms caused by Common Cold
Associated Therapies
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Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction

First Posted Date
2024-07-03
Last Posted Date
2024-07-10
Lead Sponsor
United States Naval Medical Center, San Diego
Target Recruit Count
80
Registration Number
NCT06484439
Locations
🇺🇸

Naval Medical Center San Diego, San Diego, California, United States

5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial

First Posted Date
2024-01-31
Last Posted Date
2024-05-07
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
150
Registration Number
NCT06232577
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

First Posted Date
2018-07-06
Last Posted Date
2024-06-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
43
Registration Number
NCT03579446
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Bandage Contact Lenses for Corneal Abrasions

First Posted Date
2017-07-02
Last Posted Date
2018-02-01
Lead Sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Target Recruit Count
60
Registration Number
NCT03206723
Locations
🇺🇸

Harbor-UCLA Medical Center, Torrance, California, United States

A Four-Period, Four-Treatment, Four-Way Relative Bioavailability Study of CL-108 Under Fed and Fasted Conditions

First Posted Date
2015-06-09
Last Posted Date
2017-05-02
Lead Sponsor
Charleston Laboratories, Inc
Target Recruit Count
20
Registration Number
NCT02465866

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

First Posted Date
2014-05-13
Last Posted Date
2014-05-13
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
12
Registration Number
NCT02136784
Locations
🇺🇸

UCLA Integrated Substance Abuse Programs Outpatient Clinical Research Center, Los Angeles, California, United States

Emergency Department (ED) Drug Interaction in Emergency Department Patients

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2013-05-22
Last Posted Date
2016-05-05
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
502
Registration Number
NCT01859715
Locations
🇺🇸

University of Colorado, Aurora, Colorado, United States

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