Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration

Not Applicable

Completed

Conditions: Postoperative Pain

Interventions: Drug: Ropivacaine
Drug: Epinephrine

First Posted Date: 2016-01-18

Last Posted Date: 2018-11-29

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 60

Registration Number: NCT02658240

Locations: 🇺🇸
UTSW Parkland Health Hospital System, Dallas, Texas, United States

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

Phase 4

Completed

Conditions: Arthroplasty
Osteoarthritis

Interventions: Drug: Ropivacaine with NaCl
Drug: Epinephrine
Drug: Morphine
Drug: Ketorolac Tromethamine
Drug: Ropivacaine

First Posted Date: 2016-01-18

Last Posted Date: 2018-05-09

Lead Sponsor: William Beaumont Hospitals

Target Recruit Count: 100

Registration Number: NCT02658149

Locations: 🇺🇸
Beaumont Hospital, Royal Oak, Michigan, United States

Costoclavicular vs Paracoracoid Approach to Infraclavicular Brachial Plexus Block: a Feasibility Study

Not Applicable

Completed

Conditions: Upper Limb Injury

Interventions: Drug: Ropivacaine
Device: Ultrasound

First Posted Date: 2016-01-15

Last Posted Date: 2021-01-20

Lead Sponsor: Lawson Health Research Institute

Target Recruit Count: 70

Registration Number: NCT02657291

Locations: 🇨🇦
St. Joseph's Hospital, London, Ontario, Canada

Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption

Phase 3

Completed

Conditions: Locoregional Analgesia in Breast Surgery

Interventions: Drug: Ropivacaine
Drug: Sodium Chloride
Drug: Clonidine

First Posted Date: 2016-01-14

Last Posted Date: 2021-01-27

Lead Sponsor: Jules Bordet Institute

Target Recruit Count: 54

Registration Number: NCT02655965

Locations: 🇧🇪
Institut Jules Bordet, Bruxelles, Belgium

the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block

Phase 4

Completed

Conditions: Opioid Use, Unspecified

Interventions: Drug: Ropivacaine
Drug: Dexmedetomidine
Drug: Dexamethasone

First Posted Date: 2016-01-12

Last Posted Date: 2020-07-22

Lead Sponsor: Montefiore Medical Center

Target Recruit Count: 105

Registration Number: NCT02653144

Locations: 🇺🇸
Montefiore Medical Center, Bronx, New York, United States

TAP Block for Postoperative Pain Control

Phase 3

Terminated

Conditions: Pain, Postoperative

Interventions: Drug: Exparel®
Drug: Bupivacaine
Drug: Ropivacaine

First Posted Date: 2016-01-11

Last Posted Date: 2018-11-02

Lead Sponsor: Joshua Herskovic

Target Recruit Count: 14

Registration Number: NCT02652156

Local Infiltration With Ropivacaine Improves Postoperative Pain Control in Patients

Not Applicable

Completed

Conditions: Postoperative Pain

Interventions: Drug: Ropivacaine
Drug: 0.9% saline

First Posted Date: 2016-01-07

Last Posted Date: 2018-07-26

Lead Sponsor: Air Force Military Medical University, China

Target Recruit Count: 140

Registration Number: NCT02649179

Locations: 🇨🇳
Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China

Spinal Versus Epidural Analgesia in Laparotomic Liver Surgery

Not Applicable

Conditions: Liver Diseases
Liver Neoplasms
Secondary Malignant Neoplasm of Liver

Interventions: Procedure: Spinal analgesia
Procedure: Epidural analgesia
Procedure: Transversus Abdominis Plane block
Procedure: Surgical wound infiltration
Drug: Acetaminophen
Drug: Sufentanil
Drug: Ketorolac
Drug: Ropivacaine

First Posted Date: 2016-01-06

Last Posted Date: 2016-01-06

Lead Sponsor: Ospedale San Raffaele

Target Recruit Count: 40

Registration Number: NCT02647047

Locations: 🇮🇹
Ospedale San Raffaele, Milano, MI, Italy

Is PECS Block Equivalent to Paravertebral Block in Preventing Postoperative Pain After Breast Surgery?

Phase 4

Completed

Conditions: Other Acute Postoperative Pain

Interventions: Procedure: Paravertebral block with ropivacaine
Procedure: PECS block with ropivacaine
Drug: Ropivacaine

First Posted Date: 2016-01-01

Last Posted Date: 2024-08-06

Lead Sponsor: Ospedale Regionale Bellinzona e Valli

Target Recruit Count: 23

Registration Number: NCT02645474

Locations: 🇨🇭
Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland

Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial)

Phase 4

Completed

Conditions: Ulna Fractures
Hand Injuries
Wrist Injuries
Radius Fractures
Forearm Injuries

Interventions: Drug: Ropivacaine + Dexmedetomidine
Drug: Ropivacaine

First Posted Date: 2015-12-15

Last Posted Date: 2016-08-12

Lead Sponsor: Guangzhou First People's Hospital

Target Recruit Count: 60

Registration Number: NCT02630290

Locations: 🇨🇳
Guangzhou First Municipal People's Hospital, Guangzhou, Guangdong, China

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