Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy
Clinical Trials
Related News

Pain Control After Total Knee Arthroplasty: Benefit In Adding Single Shot Adductor Canal Block to Existing Pain Regimen Protocol?

First Posted Date
2016-04-15
Last Posted Date
2023-10-30
Lead Sponsor
Henry Ford Health System
Target Recruit Count
128
Registration Number
NCT02740192
Locations
🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Desflurane
Drug: Isoflurane
Drug: Ephedrine
Drug: Phenylephrine
Drug: Norepinephrine
Drug: Epinephrine
Drug: Dobutamine
Drug: Dopamine
Drug: Isoproterenol
Drug: Milrinone
Drug: Atropine
Drug: Glycopyrrolate
Drug: Vasopressin
Drug: Terlipressin
Drug: Sodium Chloride 0.9%
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Fresh Frozen Plasma
Drug: Packed Red Blood Cells
Drug: Albumin solutions
Drug: Plasma-Lyte
Drug: Lidocaine
Drug: Bupivacaine
Drug: Levobupivacaine
Drug: Ropivacaine
Drug: Mepivacaine
Drug: Tetracaine
Drug: Prilocaine
Drug: Procaine
Drug: Chloroprocaine
Drug: Benzocaine
Drug: Articaine
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

The Prevention of Hypotension After Epidural Analgesia After Major Surgery

Not Applicable
Completed
Conditions
Hypotension
Pain
Interventions
Drug: Ropivacaine
Drug: Epinephrine
First Posted Date
2016-03-30
Last Posted Date
2024-07-25
Lead Sponsor
University of Florida
Target Recruit Count
66
Registration Number
NCT02722746
Locations
🇺🇸

UF Health, Gainesville, Florida, United States

Pectoral Nerves Blocks for Chronic Pain

Early Phase 1
Conditions
Breast Neoplasms
Interventions
Drug: Ropivacaine
Drug: Normal saline
First Posted Date
2016-03-25
Last Posted Date
2017-02-17
Lead Sponsor
First Affiliated Hospital Xi'an Jiaotong University
Target Recruit Count
140
Registration Number
NCT02719795
Locations
🇨🇳

First Affiliated Hosipital of Xi'an Jiaotong Univercity, Xi'an, Shaanxi, China

Posterior Capsular Injection With Femoral Nerve Block for Total Knee Arthroplasty

First Posted Date
2016-03-08
Last Posted Date
2018-10-03
Lead Sponsor
Trinity Health Of New England
Target Recruit Count
80
Registration Number
NCT02701296
Locations
🇺🇸

Saint Francis Hospital and Medical Center, Hartford, Connecticut, United States

Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia

First Posted Date
2016-03-04
Last Posted Date
2020-08-20
Lead Sponsor
Foisor Orthopedics Clinical Hospital
Target Recruit Count
180
Registration Number
NCT02698995
Locations
🇷🇴

Foisor Orthopedic Clinical Hospital, Bucharest, Romania

Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy

Phase 4
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Conditions
Anesthesia
Interventions
Drug: 0.9% Nacl
Drug: Ropivacaine
First Posted Date
2016-02-25
Last Posted Date
2018-03-06
Lead Sponsor
Fujian Provincial Hospital
Target Recruit Count
72
Registration Number
NCT02691195
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Fujian Provincial Hospital, Fuzhou, Fujian, China

Delirium in Elderly Patients With Trauma of the Hip

First Posted Date
2016-02-23
Last Posted Date
2023-08-04
Lead Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Target Recruit Count
239
Registration Number
NCT02689024
Locations
🇳🇱

Meander Medical Center, Amersfoort, Netherlands

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VU Medical Center, Amsterdam, Netherlands

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Academic Medical Center, Amsterdam, Netherlands

and more 2 locations

Bilateral Transversus Abdominis Plane Block With or Without Magnesium

Phase 4
Terminated
Conditions
Pain, Postoperative
Interventions
Drug: Magnesium Sulfate
Drug: Ropivacaine
First Posted Date
2016-02-11
Last Posted Date
2023-04-13
Lead Sponsor
Dr. Anthony Ho
Target Recruit Count
86
Registration Number
NCT02680626
Locations
🇨🇦

Kingston General Hospital, Kingston, Ontario, Canada

Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures

First Posted Date
2016-02-10
Last Posted Date
2021-02-21
Lead Sponsor
Ian Elliott Brown
Target Recruit Count
3
Registration Number
NCT02679560
Locations
🇺🇸

University of California Davis Med Center- Trauma and Acute Care Surgery, Sacramento, California, United States

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